X-Message-Number: 0033 Subject: Cryonics and You: An Introduction to Cryonics and the CryoCare Foundation From: Brian Wowk <> Date: Fri, 13 Jan 95 00:29:19 CST CRYONICS AND YOU An Introduction to Cryonics and the CryoCare Foundation by Brian Wowk for the CryoCare Foundation (c) Copyright 1994 by Brian Wowk Welcome to the Future Cryonics is about the future. It is about our personal future, the future of humanity, and the relationship between the two. Predicting the future is a dangerous business, and this booklet does not pretend to be a crystal ball. Sometimes, however, there are trends in science and technology that are so overwhelming that certain consequences seem inevitable. This booklet, and the science of cryonics, are based on a vision of the future that we at the CryoCare Foundation believe to be both foreseeable and compelling. It is a future with computers smaller than bacteria, cures for all of today's diseases, and people who live in good health and youth for centuries. If these developments sound too fantastic to be believed, you need read no further. If, however, you can imagine a future of such dramatic potential, then read on. Contents The Future of Medicine Introducing Cryonics Cryonics Today The CryoCare Foundation Cryonics Procedures Transport Cryoprotective Perfusion Long-Term Care The IPCF and Patient Advocate System Non-Ideal Scenarios Neuropreservation Cryonics and You CryoCare Membership Further Reading Common Questions The Future of Medicine What will medicine be like 100 years from now? If physicians a century ago had been asked this question, how many would have foreseen antibiotics, gene therapy, and MRI machines? Probably none. In fact no radiologist could have foreseen MRI (magnetic resonance imaging) even 30 years ago, let alone 100 years ago. The developments leading to MRI were occurring in computer science and physics labs, not radiology departments. Sometimes we have to look outside medicine to see where the next medical breakthroughs will come from. In 1959 Nobel laureate and physicist Richard Feynman presented a paper entitled, "There's Plenty of Room at the Bottom." In it, Feynman proposed building tiny machines that would build still smaller machines until individual atoms could be manipulated like building blocks. Feynman predicted that such a capability would have a profound impact on the science of biology and technology in general. In 1981 MIT engineer Eric Drexler published a technical paper, later followed by a book in 1986 ("Engines of Creation"), that outlined how protein engineering could lead to the capabilities that Feynman described. Drexler foresaw a whole new technology, which he called "nanotechnology," that would emerge from the ability to engineer materials on a molecular scale. In particular, he foresaw general purpose "assemblers" that like plant seeds would grow complex objects from simple raw materials, powerful computers the size of bacteria, and microscopic "cell repair machines" able to do surgery on individual cells. Nanotechnology and nanoscience are now virtually buzzwords, with cover stories in Science and Nature appearing regularly documenting progress in the field. The Japanese government is sponsoring a billion-dollar initiative to develop methods for engineering at the molecular level. Think tanks and major corporations in the U.S. are now employing scientists to specifically study the engineering applications of nanotechnology. While the capabilities to actually build the devices foreseen by Feynman and Drexler will emerge slowly over decades, the medical applications are already clear. Medicine today does not heal patients. It depends almost entirely on patients to heal themselves. It is not always successful. Traumatic injury, massive infection, or the genetic alterations of viruses, cancer, and aging often leave the body unable to heal itself. During the 21st century this will slowly change. Vast new arsenals of medical tools will become available. These tools will include microscopic robots able to perform surgery from within the body, engineered viruses able to repair genetic defects, and even intelligent cell repair organisms that are able to enter and heal cells one molecule at a time. Medicine will enter a new era. Detailed understanding and control of genes will allow the conquest of viruses and cancer. Systems of engineered cell repair organisms will be able to repair injuries that the body cannot heal by natural means. Specialized genetic programs will make possible the regrowth of injured or lost organs and limbs. Eventually even the genetic changes of aging itself will be understood and controlled. Lifespans will increase dramatically. This is CryoCare's vision of the future: a medicine based on mastery of the molecular basis of life. We are all made of atoms and molecules. The difference between health and disease, youth and old age, even life and death, is ultimately a difference in the arrangement of our atoms. Medicine will not reach its fullest potential to heal and restore health until it is able to analyze and rearrange atoms in sophisticated ways. Such a time is still far off. But it will come. Introducing Cryonics In 1964 physicist Robert Ettinger made a remarkable proposition. Ettinger suggested that low temperature preservation (cryopreservation) might be a way for dying patients today to reach future medicine. Tissue cooled to the temperature of liquid nitrogen (- 196'C) can be maintained for centuries, if necessary, with no change. If during this time new medical technologies become available, then cryopreserved patients could be treated with those technologies. This idea-- maintaining dying patients at low temperature for future revival and treatment-- has come to be called cryonics. Cryonics is controversial because freezing an entire body is not reversible today. Although many individual cells remain viable and able to resume function after freezing and thawing, the ice crystals that form between cells cause extensive tissue damage. This damage prevents the return of normal organ function. Freezing, according to medicine today, is a fatal injury. Will the injuries of freezing always be irreversible? This is the central question of cryonics. If the cell repair technologies of the future can heal the injuries produced by freezing today, then freezing is not truly fatal, and cryonics is a viable path to the future. Of course this is speculative, and therein lies the controversy. Cryonics Today Cryonics would have remained idle speculation to this day were it not for another idea proposed by Robert Ettinger. How could a procedure that is widely believed to be fatal be legally applied to dying patients? Ettinger's answer was to wait until a patient's breathing and heartbeat stopped before starting cryonics procedures. The patient would then be legally dead, and cryonics could do no additional harm. The rationale for applying cryonics after legal death is that legal death and +real+ death are often not the same. Patients dying of a terminal disease are usually given a "no code" or DNR ("do not resuscitate") status, which means that no attempt will be made to resuscitate them if their heart stops. This is despite the fact that often they +could+ be revived if an attempt was made. This discrepancy between legal death (stopping of the heart) and when the brain really dies creates a window of opportunity for cryonics. Although having to wait for the legal death of terminal patients creates substantial logistical (and sometimes medical) problems for cryonics, it is a perfectly legal way to implement cryonics today. At the time of writing, approximately 50 cryopreserved patients are in the care of six U.S. organizations that offer cryonics services. In addition, more than 600 other people have made the legal and financial arrangements necessary to have cryonics available for them and their families. These people include doctors, scientists, students, tradesmen, housewives and children-- people from all walks of life who share a common desire to reach beyond the limits of today's medicine. The CryoCare Foundation In 1993 a group of long-time cryonics activists and professionals gathered together. Their goal was to combine the best features of existing cryonics companies with important new features in order to create the best possible cryonics organization. The result was the CryoCare Foundation, a non-profit Delaware corporation that manages cryonics services for its members. CryoCare is a membership organization that provides cryonics services to its members by contracting with outside companies that possess special expertise in various aspects of cryonics. CryoCare was founded on the belief that excellence in cryonics can be best achieved in a competitive business-like environment that encourages individuals and companies to focus on their own areas of specialization. CryoCare and its members are then free to choose among the best resulting cryonics service companies. Cryonics Procedures A typical scenario for a human cryopreservation begins in a hospital, nursing home, or home hospice setting where a CryoCare member is seriously ill. In consultation with local physicians, the member's condition is evaluated by medical staff at BioPreservation, Inc., CryoCare's initial-response cryonics service provider, based in Rancho Cucamonga, California. BioPreservation will then dispatch a cryonics transport team to the member's location. Transport If the member's condition was terminal, legal death will be pronounced by an independent attending nurse or physician the moment the heart stops. The CryoCare member now becomes a CryoCare patient, and the cryonics transport team begins its work. The patient is lowered into an ice bath, and two minutes later circulation and breathing are artificially restored by a Heart Lung Resuscitator (CPR machine). Intravenous lines are established, and special medications are administered to protect the brain from any lack of oxygen. Thirty minutes later, major arteries and veins have been surgically accessed, and the patient is placed on cardio-pulmonary bypass. ("Bypass" means that blood is now circulated through a heart- lung machine, which takes over the function of the patient's own heart and lungs.) CPR is no longer necessary, and is discontinued. A heat exchanger in the heart-lung machine now greatly accelerates cooling to near the freezing point of water. If the patient is outside of Southern California, their blood will be replaced with an organ preservation solution, and they will be packed in ice for air shipment to BioPreservation's surgical facility near Ontario International Airport. (Transplant surgeons prepare organs for long-distance transport using similar procedures.) Cryoprotective Perfusion At BioPreservation's facility, surgery is performed to gain access to the great vessels of the heart. The organ preservation solution is then replaced with a solution containing glycerol (an anti-freeze agent) to protect against freezing injury. Once perfusion (circulation) of this cryoprotectant solution is complete, the patient is immersed in silicone oil for cooling to -79'C (dry ice temperature) over the next 48 hours. This completes the Transport and Perfusion phases of human cryopreservation as performed by BioPreservation, Inc. Long-Term Care Long-term care is the maintenance of cryonics patients for the indefinite future at -196 degrees Celsius, the temperature of liquid nitrogen. CryoCare's long-term care service provider is CryoSpan. CryoSpan is a for-profit company founded in 1993 that specializes in providing long-term care of cryonics patients on a contract basis with cryonics membership organizations, such as CryoCare. CryoSpan is located in the same facility as BioPreservation, Inc., although it is an independently owned and operated company. CryoSpan has recently completed construction of an underground storage vault that has been certified by seismic engineers to withstand even major earthquakes. CryoSpan is the only cryonics care facility to offer vault protection of all its patients against fire, vandalism, or earthquakes. CryoSpan currently cares for two patients. Following initial Transport and Perfusion by BioPreservation, CryoCare patients are transported at dry ice temperature to the long- term care provider of their choice. They are then slowly cooled over a two week period to the temperature of liquid nitrogen (-196'C), and immersed in liquid nitrogen for long-term care. At this temperature all biological processes are stopped, and tissue remains unchanged virtually indefinitely. CryoCare retains legal custody of its patients. If the patient's funds are sufficient, CryoCare has the power to transfer a patient to the long-term care of another company if necessary. CryoCare patients are thus protected from business failures or other failures of long-term care providers. The IPCF and Patient Advocate System CryoCare has established a separate non-profit organization called the Independent Patient Care Foundation to administer the funds that patients leave for their long-term care. The IPCF exists solely for the purpose of safeguarding the long-term care funds of CryoCare patients, and will employ professional money managers to invest patient funds for security and long term growth. The IPCF bylaws require it to disburse funds for patient care and administration only. No exceptions are permitted. It is the intention of CryoCare and the IPCF to account for patient funds individually. This means that money you set aside for your care pays for your care only, and is not pooled with funds from other patients. It is also the intention of CryoCare to return to you any left over, or "walkaway" funds, should you ever be revived. These unique features of CryoCare create complex legal and tax issues. Briefly, CryoCare and the IPCF are in the process of applying for tax- exempt 501(c)13 status with the U.S. Internal Revenue Service. Minimum cryopreservation funding for all patients would fall under 501(c)13 tax exemption, and amounts above minimum would be placed in individual trusts either offshore or in the state of Wisconsin, which has no rule against perpetuities. If the 501(c)13 application is unsuccessful, several other alternatives to minimize taxes and maximize fund protection are available. A fuller discussion of these issues can be found in the CryoCare discussion paper, "Corporate/Trust Structures for Long-term Care and Restoration Funds." CryoCare is the only cryonics organization with a system of Patient Advocacy. A Patient Advocate is an individual, group of individuals, or organization that you optionally appoint to oversee your care after you are cryopreserved. Patient Advocates serve as "watchdogs" to ensure that CryoCare always looks out for your best interests when you can no longer speak for yourself. Patient Advocates have the power to vote for a special class of CryoCare directors called Patient Directors, who vote on issues related to patient care. Patient Advocates also have the power to initiate the transfer of a patient under their supervision from one long-term care company to another. Non-Ideal Scenarios In some cases, particularly when sudden death is involved, it is not possible to begin cryonics procedures promptly after the heart stops. There may be a wait of many minutes, or even hours before cooling can begin. Brain injury is severe in such cases. By today's medical criteria, anyone whose blood circulation has been stopped for an hour is very "dead." The question we must ask, however, is what will future medicine define as "death." Today's medicine cannot revive people after the heart has been stopped for much longer than five minutes. This is because injuries to blood vessels within the brain (such as blood clotting) prevent circulation from being restored after five minutes. Surprisingly, individual brain cells (neurons) remain alive and able to resume function for as long as an hour after the heart stops. If future medicine can heal and replace injured blood vessels, then it should be able to resuscitate people far beyond today's time limits. If it can use microscopic devices to reverse chemical imbalances within injured cells, then there is no apparent reason it could not revive people after an hour or more of clinical death. With a view toward advanced future medicine, it is difficult to say where the outer limits of resuscitation will be. It is for this reason that cryonics is still applied to patients who are far beyond the reach of today's medicine. It would be extremely short-sighted and arrogant for us to believe that medicine today is the best medicine that could ever exist. This is why cryonics is medically +conservative+. Continuing to care for a patient with an uncertain prognosis is the morally and ethically correct thing to do. Many patients that we would call "dead" today are likely to be reclassified as "seriously ill, but treatable" in the future. Neuropreservation Cryonics is an expensive and speculative route to the future. A large part of the expense is providing sufficient principal to pay for indefinitely long care. This has led some people to ask what the bare minimum requirements are for cryonics to work. One of the lessons that modern medicine has taught us well is that our most irreplaceable organ is our brain. We can transplant hearts, livers, kidneys, and lungs (sometime simultaneously!). We can suffer severed spinal cords. We can lose limbs. Yet all these events, with whatever impairments might result, still leave us as +ourselves+. In contrast, even minor injuries to the brain can fundamentally change +who we are+. Taken to the extreme, death of the brain is the absolute and incontrovertible death of the person. No other organ has this property. Our brain is the most unique and personal thing we will ever possess. Future medicine will have vast and general capabilities for tissue repair and regeneration. The healing of spinal injuries and regrowth of lost limbs and organs will be straightforward for a technology with detailed understanding and control of gene expression. The challenge of repairing a brain with extensive microscopic freezing injury will be much more formidable. It is arguable that by the time technologies are developed for repairing freezing injury to the brain, complete regrowth of a healthy new body for the healed brain will be a minor exercise. How do we know that growing a new body "from scratch" is possible? First, the ability to do so is implicit in a technology that can understand and manipulate genes. Second, and perhaps more to the point, +the growth of a new body starting from a single cell is a technology already demonstrated in nature+. That "technology" is how we got the body that we now have. Imagine the newly healed brain of a cryonics patient, suspended in the fluid of a 22nd century "artificial womb." Genetic reprogramming of a single cell on the surface of that brain begins a process of growth and development that perhaps a year later surrounds the brain with a complete young adult body. This is the rationale for neuropreservation, which is cryopreservation of the brain. Neuropatients consume one-tenth the volume and one-tenth the maintenance expense of whole-body patients. Neuropreservation is therefore a significantly less expensive form of cryonics. Even when sufficient funds for whole-body cryopreservation are available, the same amount of funding will in general offer a neuropatient ten times the security of a whole body patient. Many CryoCare members have chosen the neuropreservation option. In addition, all CryoCare members who choose whole-body cryopreservation must consent to emergency conversion to neuropreservation if future economic problems or other difficulties make such conversion necessary for continued care. CryoCare will not allow the loss of a whole-body patient as long as the neuro option remains available. The physical procedures followed during the cryopreservation of neuropatients are similar to those outlined above for whole body patients. Following the completion of cryoprotective perfusion at BioPreservation, cephalic isolation is performed between the sixth and seventh cervical vertebrae. Because the brain by itself is an extremely fragile organ, it is maintained within the head for protection and security. Non-preserved remains are disposed of in accordance with the patient's wishes. Cryonics and You What is your vision of the future? Some people see a future of overpopulation, resource depletion, and environmental ruin. Some people see a future not very different from the world today. Some people, perhaps most people, don't think about the future at all. At CryoCare, we believe that the next one hundred years will bring more technological change than perhaps the last thousand years. These changes will render most of today's ideas about resources, population, and medicine quaint and obsolete. The result may be a world where people for the first time in history have the time and resources to enjoy life without the prospect of progressive physical decline and imminent death. It may also be a world with frontiers that extend to the stars. We plan for such a future now not because it is certain, but because it is +physically possible+. At CryoCare, we believe that there is no higher value than that of an individual human life. If a doorway exists, or can be created, for reaching the future from today, we are prepared to step through that door when there is no other choice. We invite you to join us. For more information, call or write: CryoCare 10627 Youngworth Road Culver City, CA 90230 U.S.A 1-800-TOP-CARE CryoCare Membership For $30 a year, Associate Members of CryoCare receive CryoCare's quarterly newsletter, CryoCare Report. CryoCare Report features news, opinion, and technical developments related to the practice of cryonics. For $350 a year, you can make cryonics services available to yourself and your family by becoming a Cryopreservation Member of CryoCare. Additional family members may join for $250 a year, or $125 for children under 15. Students may become Cryopreservation Members for $175 a year. These annual membership dues help support emergency readiness at BioPreservation, Inc., as well as CryoCare's own administration. There is also a one-time-only $100 sign-up fee. (This fee is waived if you are already a member, or in the process of becoming a member, of another cryonics organization.) In addition, CryoCare requires that Cryopreservation Members provide a guaranteed source of funds to pay for their cryopreservation. These funds can be in the form of a trust, or more commonly, ordinary life insurance. Life insurance sufficient to fund cryonics arrangements can be surprisingly inexpensive, especially if you are young and healthy. Call your insurance agent or CryoCare for more information. Minimum funding requirements depend on the long-term care provider that you prefer. For care at CryoSpan, current minimums are $125,000 for whole body cryopreservation, and $58,500 for neuropreservation. After the up-front costs of cryopreservation are disbursed (approximately $40,000), the remaining principal is managed by the IPCF to produce revenue that pays billings from CryoSpan on an annual basis. CryoCare has set its funding minimums for care at CryoSpan based on a conservative assumption of 2% annual return on investments after inflation. Movement from CryoSpan to another long-term care provider (if ever necessary) is expected to always be possible because the principal is not depleted. If you choose the Cryonics Institute (CI) for long-term care, the current minimum funding requirement is $95,000 for whole body cryopreservation or $69,000 for neuropreservation. After the up-front costs of cryopreservation are disbursed, CI charges CryoCare a one- time fee of $28,000 for whole-body patients and $10,000 for neuropatients for long-term care. The remaining principal is held for the patient by the IPCF to pay for care elsewhere if ever required. CryoCare members desiring long-term care at CI must also become CI members, which requires a one-time-only payment of $1250 per person, or $1875 per couple, payable at the time of joining. CryoCare strongly advises its members to arrange funding greater than the current minimums. Newer, more expensive technology as well as inflation will certainly increase minimum funding levels in future years. Members not able to meet new minimums will be required to cancel their arrangements. Further Reading Non-Technical Books Engines of Creation (Anchor Press, 1986) by K. Eric Drexler (Highly Recommended) Unbounding the Future (Morrow, 1991) by K. Eric Drexler with Gail Pergamit Monographs (available from CryoCare) Many Are Cold But Few Are Frozen: A Humanist Looks at Cryonics by Steven B. Harris, M.D. Will Cryonics Work?: Examining The Probabilities, by Steven B. Harris, M.D. Technical Books Nanosystems (Wiley & Sons, 1992) by K. Eric Drexler, Ph.D. Published Papers Drexler K E, Molecular Engineering: An Approach to the Development of General Capabilities for Molecular Manipulation, PNAS (USA), 78: 5275-5278 (1981) Merkle R C, The Technical Feasibility of Cryonics, Medical Hypotheses, 39: 6-16 (1992) Monographs (available from CryoCare) The Cryobiological Case for Cryonics, by Gregory Fahy, Ph.D. A "Realistic" Scenario for Nanotechnological Repair of the Frozen Human Brain by Gregory Fahy, Ph.D. Common Questions Science Questions: Doesn't freezing burst cells, like water freezing in a bottle? No. Slow cooling causes ice to form outside cells first. This causes an increased concentration of salts outside cells, which draws water out of cells, dehydrating them. At the end of freezing, the space between cells is filled with ice crystals, but cells themselves remain unfrozen (vitreous) in their interior. Ice crystals outside cells still cause damage, but not as much damage as would be caused by ice inside cells. Can humans be frozen and revived? Humans can only be frozen, they cannot be revived with today's technology. The purpose of cryonics is to carry people to future technology that will be able to revive and treat them. If no one has been revived yet, then isn't cryonics unproven and unscientific? Cryonics is unproven, but it is not unscientific. Cryonics depends on foreseeable medical advances, not blind faith in the future. In 1961, when the United States committed itself to landing a person on the moon, there was no proof this could be done. It had never been done before. Nevertheless it was concluded from known principles of science and engineering that such a feat was possible. The space program, human genome project, freezing the DNA of endangered species for future cloning, are all projects that were begun based on the expectation of foreseeable technologies that did not yet exist. Like cryonics, they are scientific undertakings not acts of faith. Won't memories be lost if a brain stops working, like turning off a computer? No. Neuroscientists agree that long-term memory is stored by durable structural and molecular changes within the brain, not transient electrical activity. In fact there are many situations in clinical medicine today in which a patient's brain is stopped and restarted with no lasting harm. These situations include ischemia (stopped blood circulation), deep hypothermia, and deep anesthesia. Isn't freezing after legal death too late? In many cases it is possible to have a cryonics transport team standing by during the final stages of a terminal illness. CPR and administration of stabilizing medications can begin within a minute or two after breathing and heartbeat stop (legal death). Under such favorable circumstances, brain injury can be so minor that there would be no difference even if cryonics procedures were begun before legal death. It is also possible that cryonics may still work even if legal death occurred many minutes (perhaps even hours) earlier. There are published reports in the scientific literature of viable brain cells sometimes being found hours after legal death. Some so-called "dead" patients today may in fact still be treatable by far future medicine. (From a cryonics standpoint, the chief problem caused by protracted clinical death is failure of the brain's circulatory system. This prevents good cryoprotective perfusion, greatly worsening freezing injury.) Does this mean that future medicine might be able to bring back the dead? Not at all. If patients in the future can be recovered after hours of +clinical+ death, it will simply mean that medicine today is wrong about when it thinks death really happens. When considering these questions it is helpful to remember that death is usually a +process+, not an event. The most difficult cryonics scenarios are those involving chronic degenerative brain diseases (such as Alzheimers), or protracted respirator support of severely brain injured patients. By the time legal death is declared in such cases, loss of brain structure can be so extensive that these patients are dead by +any+ medical criteria, present or future. To counter these possibilities, CryoCare recommends that individuals take legal steps (such signing a Durable Power of Attorney for Health Care) to ensure that medical measures such as life support are never utilized in a manner that violates their wishes for timely cryopreservation. Is research being done? What improvements can be expected? At the time of writing, small privately-funded cryonics research projects are being pursued by BioPreservation, Inc. in California, the Alcor Life Extension Foundation in Arizona, and the Cryonics Institute in Michigan. These initiatives are directly aimed at better understanding and improving cryopreservation of the human brain. Unfortunately no government agencies or other conventional funding sources have an interest in brain cryopreservation. There is, however, some wider interest in cryopreservation of the kidney, heart, liver, and other transplantable organs. In recent years great strides have been made toward reversible cryopreservation of the kidney. The most promising approach is called vitrification. Vitrification is cryopreservation without formation of damaging ice crystals. CryoCare is hopeful that vitrification will be used to achieve reversible (non-injurious) preservation of the human brain within the next decade. If successful, this technology would be perhaps the most important medical breakthrough of our time-- an assured means to transport the most essential part of ourselves (our minds) to any point in the future. Social Questions: Why would anyone want to live beyond their natural lifespan? "Natural lifespan" is a relative term. Today we consider a natural lifespan to be about 75 years because this is how long the average person lives in the industrialized world. Someone from the Middle Ages (with a life expectancy of 30 years) would regard today's medicines and lifespans as extremely unnatural. A century from now, people will probably look back on the lifespans of the 20th century with amazement and even pity as they look forward to centuries of life, health, and youth. Why would people of the future revive cryonics patients? Cryonics patients are not being cast adrift upon a sea until some future historian finds them. They are being cared for continuously by an organization (such as the CryoCare Foundation) with the express purpose of reviving them. If a patient stays frozen long enough for revival technology to be developed, it will be because they are still in the care of an organization that intends to revive them. In other words, revival will happen (if it happens) because someone cared enough about your revival to keep you frozen. It will not really matter what the rest of future society thinks. How will future society likely regard cryonics patients? By the time it is possible to revive today's patients, future medicine will already have a long tradition of treating patients in "suspended animation" and other forms of biostasis. Today's cryonics patients would be morally equivalent to any other injured patient who needs help in that era, and will likely be regarded as such. When will cryonics patients be revived? When you are revived will depend on when you were frozen. Cryonics will be a last-in-first-out process. Patients preserved with the most advanced technology will require the least treatment. At some point, perhaps 50 years from now, completely reversible "suspended animation" will likely be developed. The wait for revival for such patients will be zero; they will be revivable at any time. Patients frozen before suspended animation is developed will have to wait for revival. The older the technology used, the longer the wait will be. Today's cryonics patients are severely injured, even by future medical standards. Although there are reasons for optimism, the wait will be long. Comprehensive cell repair systems based on mature nanotechnology will have to be developed. Cells will have to be repaired individually, in some cases even one molecule at a time. Responsible estimates of the time required to develop such technology range from 100 to 200 years. What will the future be like? Many futures are possible. Not all possible futures (particularly the bad ones) are compatible with revival of cryonics patients. This has interesting implications. For instance, the simple fact that you stayed frozen long enough to get revived means that civilization did not collapse. Human progress must have continued its unsteady march forward, reaching a level of very advanced medical technology. The world must also be a be reasonably comfortable, safe place. If it were not, the people reviving you would be preoccupied with their own problems instead of yours. Advanced nanotechnology, as foreseen by Drexler, Feynman and others, must also be a reality. Among other things, this technology implies: * Computers thousands of times faster, and millions of times smaller than today. * Self-reproducing manufacturing systems able to produce mass quantities of most any product at near zero cost. * Per capita wealth perhaps a thousand times greater than today. * Lifespans with no natural limit. * A spacefaring civilization. If cryonics works, it will work in a world that is much bigger, wealthier, and more interesting than the one we know today. Ethical Questions: Doesn't cryonics contribute to overpopulation? Currently about three children are born for every one person who dies. Rushing people off to an early grave is not going to solve this problem. Birthrates must be reduced to sustainable levels. This has already happened in the industrialized world, where population is generally not a problem. If past trends continue, birthrates will eventually drop in poorer nations as they too become more industrialized. Longer life spans in rich countries will not hinder this process, and eventually all the world will benefit. Isn't cryonics an expensive extravagance? The cost of cryonics is comparable to the cost of other major medical procedures today. It is affordable for most middle class people who can buy life insurance. What happens to the soul of a frozen person? What happens to the soul of a person who is awakened after many decades in a coma? Most people would say that the soul was dormant, or asleep in God's care, until it was time to wake again. In fact many babies have been born after years of frozen storage in liquid nitrogen (while they were embryos). Revival of frozen embryos is not resurrection, and neither is cryonics. If cryonics works it will simply mean that cryonics patients were never really dead in the first place. They were instead in a kind of coma that today's primitive medicine mistakenly calls death. Medical definitions of death have changed several times this century. These definitions are bound to change even more during the next century. Does cryonics conflict with religious beliefs? Medical advances that increase the quality and length of our lives are usually embraced by most religions. If life in this world has a purpose and value, then acting to preserve that life by reasonable means is morally valid. Is cryonics a reasonable means? This is a question we must each answer for ourselves. Acceptance of new medical ideas is sometimes slow. There was once a time when many people considered surgery (or even anesthesia during surgery) to be unreasonable and against God's will. Today we take painless surgery for granted. Cryonics may also require a long time to achieve wide public acceptance. In the meantime we must strive to evaluate cryonics according to its own merits. Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=0033