X-Message-Number: 10644
Date: Sun, 25 Oct 1998 15:38:52 -0700
From: Mike Perry <>
Subject: Re: CR an aging decelerator?

Last time I said (#10640)

> ... despite the increase
>in longevity that is seen under known conditions of CR, there is still some
>uncertainty as to whether it is "really" what we would call an "aging
>decelerator" leading to a true increase in maximum lifespan, or just a
>turnoff of aging accelerators.

But it appears this "uncertainty" is not real after all, in view of Brian
Delaney's response (#10639) that female CR'd mice are unable to conceive,
i.e. wild mice could not be naturally CR'd in the same sense. Perhaps it
doesn't quite "prove" that CR is an aging decelerator, but the evidence does
strongly point that way, by appearances. Thanks, Brian, for this--I'd be
interested in a reference too (answer me privately if you wish).

Mike Perry

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