X-Message-Number: 10891
Date: Tue, 8 Dec 1998 05:09:08 -0800 (PST)
From: Doug Skrecky <>
Subject: Re: peanuts improve lipoproteins

>"Low Fat-monosaturated Rich Diets Containing High-oleic Peanuts Improve
>Serum Lipoprotein Profiles."
>Lipids 32(7): 687-695 Jul 1997
>
>Abstract:
>
>  Postmenopausal hypercholesterolemic women are at risk for cardiovascular
>disease and are encouraged to follow low-fat (LF) (< or = 30% energy)
>diets. However, these diets may have undesirable effects on high density
>lipoprotein cholesterol (HDL-C), apolipoprotein A-I (apo A-I) and
>triglycerides, whereas diets high in monosaturated fats do not. Twenty
>postmenopausal hypercholesterolemic women previously consuming high-fat
>diets (34% energy) were placed on a low fat-monosaturated rich diet (LFMR:
>26% 14% energy, respectively) for 6 mon. Sixteen women already eating LF
>diets (24% energy) were also followed to monitor variations in serum lipids
>due to seasonal variations. Twenty-five women successfully completely the
>study (LFMR = 12, LF = 13). Serum cholesterol decreased 10% (264 to 238
>mg/dl, P< or = 0.01) and low density lipoprotein cholesterol (LDL-C)
>decreased 12% (182 to 161 mg/dl, P < or = 0.01) in the LFMR group, but did
>not change in the LF group. The reduction in serum cholesterol in the LFMR
>group was greater than estimated by predictive formulas. Serum
>triglycerides and apo A-I did not change in both groups, but only the LFMR
>group showed a trend toward toward beneficial changes in LDL-C/HDL-C and
>apo A-Vapo B ratios. Overall, the LFMR was well tolerated and resulted and
>resulted in an improved serum lipid and apolipprotein profile.

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