X-Message-Number: 11000
Date: Wed, 30 Dec 1998 23:58:16 -0800
From: Keith Rene Dugue <>
Subject: Vitrification and Thermal stress

To: Thomas Donaldson  Thermal stress is caused by differential
coefficients of expansion and/or temperature gradients. Assuming the brain
can be cooled isothermally ,differing coefficients of expansion in the
brain should still cause some  thermal stress. How can this be eliminated
or reduced? 21st Century Medicine's Synthetic Ice Blocker 21CM-X reduces 
Ice crystal formation. This will not eliminate the coefficient of
expansion differential due to varying concentrations of water/glycerol  in
the different structures of the brain.  

I had the fortunate pleasure of speaking ,at some length, with Dr. Fahey
about inhibiting ice formation. He seemed to think that  they could
squeeze some more performance out of their synthetic ice blocker
technology. Of course ,he did not discuss any specifics of their
proprietary work. I was very impressed to say the least ;however, I still
don't understand how the coefficient of expansion differential will be
eliminated  or reduced to a level that will prevent brain cracking by even
perfect vitrification.  

Keith R. Dugué  

NO SPAM -----BEGIN PGP PUBLIC KEY BLOCK----- Version: PGPfreeware 5.5.5
for non-commercial use <http://www.nai.com> Comment: !!! PLEASE STORE THIS
FILE ENCRYPTED !!!  
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 =JwJm -----END PGP PUBLIC KEY BLOCK-----  

Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=11000