X-Message-Number: 11605 From: Date: Fri, 23 Apr 1999 21:48:33 -0500 (CDT) Subject: Book Review: The Heart Revolution Book Review: The Heart Revolution by Kilmer McCully, M.D. (1999; HarperCollins Publishers, NY; ISBN: 0-06-019237-2) I got four messages from reading this book. They are: Primary message: By taking a cheap, daily multi-B vitamin pill (which includes B-6, B-12 and folic acid) heart disease can be arrested or prevented. (Vitamins E, C and balanced bulk and trace minerals are also recommended as advisable). Secondary message: Thirty years of medical evidence indicate that elevated levels of the amino acid homocysteine directly cause damage to arteries, "leaving them susceptible to cholesterol and fat deposits". Dietary cholesterol is not the cause. Political message: The medical-pharmaceutical-industrial complex can and does strive to supress health discoveries which might undercut expensive drug and surgical therapy alternatives. (They WILL let you die to make money). Cryonics message: Take a cheap multi-B vitamin daily as it will not hurt you and it may prove to be very, very helpful to extend your life. (This follows the Cryonics formula: Small known cost now, large potential payoff later). Summary: In 1968, Harvard-trained medical researcher Kilmer McCully discovered the association between homocysteine and arteriosclerosis based on an index case first published in the New England Journal of Medicine in 1933. When McCully began publishing his findings in the early 70's he ran full in the face of the politally-approved anti-cholesterol public propaganda movement. Following the publishing of his initial findings, McCully lost his grant support, as well as his appointments at both Harvard and Massachusetts General Hospital. The old story of trying to kill the messenger. Fortunately, despite successful efforts to squash McCully's research efforts, other researchers in Sweden, Norway, the Netherlands and Ireland confirmed his hypothesis years later. Finally in the 1990s, two major United States research groups, the Physicians Health Study and the Framingham Study, found clear correlations between homocysteine levels and heart disease which were then published in The New England Journal of Medicine and the Journal of the American Medical Association. The old story of trying to revive and reclaim the messenger as your own. Before you are tempted to dismiss McCully's ideas, understand that while his suggestions may seem simplistic at first glance, his tone is calm, his reasoning balanced and his research impeccable. And sometimes simple things work (washing hands before surgery, eating limes to prevent scurvy, thinking before expressing opinions, etc.). McCully recommends obtaining one's B vitamins from food selection (and avoiding processed foods) rather than just turning to a supplemental vitamin pill, as there may very well be other critical elements good for health not yet discovered. (How ridiculous!) He also wants to move the patient away from simply popping a B vitamin pill while not making any dietary choices at all. (What! NOT eat a Big Mac and fries every day! What nonsense!). The book is short (190 pages) and written for popular consumption. Page 117 lists his recommended levels of supplementation based upon disease symptomology and plasma homocysteine levels. Chapter 8 deals with issues involving aging and chapter 9 examines homocysteine as the possible major cause of Alzeimer's disease, fibromyalgia, chronic fatigue symdrome, and some autoimmune diseases. I found the book refreshing and thoughtful. Presenting evidence that the homocysteine connection can explain not only why the Mediterranean diet can be high in fat but low in heart disease statistics, as well as suggesting that the failue of aging cells to produce sufficient levels of thioretinaco ozonide (a compound made of homocysteine, vitamin A, vitamin B12 and ozone) IN the cells is the PRIMARY cause of aging, made for fascinating reading. From page 176, McCully writes, "I can't promise that your wrinkles will go away, your gray hair will disappear, and your energy will be the same today as it was when you were twenty. But the Heart Revolution can slow down the aging process - considerably - and prevent disease - definitely. You'll live longer, be healthier, and age more gracefully." I hope others will read and comment on this book. Right now, I have to go take my vitamins. -George Smith Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=11605