X-Message-Number: 1296 Date: 11 Oct 92 06:26:46 EDT From: "Steven B. Harris" <> Subject: Talk of Sacred Things Aloud... >>Along with Charles Platt I did not find Edgar Swank's long message dull or boring, but I do feel that it could have been spread out. I like the idea of summarizing large postings so we can ask for more details.<< Comment: Yes... but the difficulty with such messages is, as Emily Dickinson once complained, that "they talk of sacred things aloud, and embarrass my cat." Which is to say that the real problem with the BBS material in question was perhaps not so much length, or lack of summary per se, or lack of interest; but rather a psychological stickiness of Freudian proportions. Do we really need, for instance, to read about Jerry White gently massaging his mother? And if so, do we need (for lack of an editor) to read again and again about Jerry White gently massaging his mother? "But hail!" writes Jerry to his mother, "You, the fragile glory of animalhood! You, belly that kindled and held me, portal that birthed me, breasts that fed me..." etc. The subject obviously interests Jerry, but the rest of us BBS readers were in a severe struggle to keep from losing it long before we got to the mouth-to-mouth sequence. Possibly there should be a warning in front of the really nails-on-blackboard-maudlin stuff? This of course being what everyone here on the Net has obliquely been asking for (i.e., a sort of emotional-pornography warning label for certain cryonics essays, in the form of a summary), but without quite coming out and saying it. Okay, so now I'm saying it. Where is Tipper Gore when we cryonicists need her? ;-} I do want to say, by the way, that this whole episode brought to mind Edgar Swank's assertion on this BBS not long ago that there were several people in ACS who had contracted for the mortuary-perfusion-brain-removal-by-pathologist cryonics option, and THAT THESE PEOPLE were entirely satisfied and happy about it. At the time, there wasn't much I could say to that, though I was dumfounded. Reading Mr. White's piece about this sort of thing in practice, however, I have to say that among many feelings there I did not quite get the feeling that he was entirely happy and satisfied about what happened. On the contrary, I saw painted a picture of someone who was not only left alone to try to do the resuscitation of his mother with equipment that didn't work, but who also discovered at the end that his mother's brain had not been perfused uniformly, because of a poorly designed protocol. If Jerry got this deal for a cut rate, he might have gotten good value depending on how much he paid (say, are all the ACS brain-only and HIV people funded at pauper rates?), but on the other hand, if all this went down for the full ACS neuro price then in my opinion Jerry got a really bum deal, since for the same money he could have had Alcor do a decent job. Once upon a time here on CryoNet I pointed out that the idea of perfusing people through carotids alone was a bad idea because the hind brain is perfused through the vertebrals, and in 75% of people the connections between forebrain and hindbrain circula- tion are less than perfect. At the time, Mr. Swank said he did not understand me due to technical medical jargon, so here it is again in words of a few syllables: Four vessels feed the brain, and these four vessels are con- nected perfectly to each other at the base of the brain (in a fully-formed "circle of Willis") in only 25% of people. The other 75% of people are probably best perfused through all four vessels. That means open chest surgery to isolate the ascending aorta. Mr. White & Co. discovered that one carotid is not enough (duh-- surprise) but the lesson is in fact more general. Even both carotids will not be enough for most people, judging by both Alcor's dog work and the known facts of human neurovascular anatomy. The problem with cryonics (as has often been remarked) is that there is too little quality control, because in cryonics no one is really sure in many cases just what "quality" is. It is safe to say, however, that you'd like to know that you have some given concentration of glycerol or other cryoprotectant in a brain before you cool it to cryogenic temperatures, and you'd also like to know that this given concentration is reasonably uniform throughout the brain. At Alcor, we get at these questions by controlling the entire 4-vessel --> 3-vessel circulation to the brain in every suspension, and by measuring the glycerol con- centrations in venous return from the brain so we know how much got in. I've yet to see evidence of both of these crucial operations being done together ever at other cryonics organiza- tions, where in contrast the philosophy often seems to be: stick a needle in, pump solution for a while, pray, and freeze. Always the same story. Worse still, I'm afraid that I'm condemned to have to *download* this story in various forms again and again and again in future years at a price (call 1-900-CRYO-EEK), thanks to Ed Swank and the miracle of the modern computer. And all without a single pornography warning label, too. Steve Harris Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=1296