X-Message-Number: 13368 Date: Tue, 7 Mar 2000 06:02:41 -0500 From: Thomas Donaldson <> Subject: CryoNet #13364 - #13366 Hi again It is interesting that de Gray, the author of the book discussed by Ettinger, has noticed that deprenyl actually has experiments showing an increase in MAXIMUM lifespan. That is actually true; and other drugs affecting lifespan also have that characteristic, though not all of them. The statistics required to establish that a drug treatment increases MAXIMUM lifespan is much more extensive than that needed to simply show that it increases average lifespan --- mainly because in most experiments only a few animals come close to maximum lifespan, and we need more than a few to establish whether or not a drug will increase maximum lifespan. I will try to obtain this book myself, though I personally am dubious that oxidation accounts for all the breakdowns of aging. One problem with such a theory is that it must also account for other changes that happen with aging. I'm hardly claiming that oxidation does not account for SOME significant changes, only that it is not the whole story. Best and long long life to all, Thomas Donaldson Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=13368