X-Message-Number: 1429 Date: Sat, 12 Dec 92 16:47 PST From: (Keith Lofstrom) Subject: CRYONICS - Skull removal during suspension A lot of "why won't this work?" questions are being answered gently and well, so I thought I would ask one of my own: Why are we preserving skulls with the brains? I can imagine a suspension team ( probably with more surgical skill than we are currently blessed with) removing most of the skull, leaving the ridge above the eyes and bone around the ears to act as structural support (saving all the pieces, of course) and opening the exposed dura mater, then plunging the whole thing into an appropriate perfusion bath. Why? Well, it may be easier to reach parts of the brain with perfusant through the folds in the brain than through the circulatory system, or perhaps easier through both approaches in parallel. I imagine the bath would have to be pressurized at the arterial pressure of the pump driving the perfusant through the circulatory system. Since partial skull removal is something we *already* can deal with medically, the major downside risk I can see is accidental damage to the exposed brain, through mishandling, or too-vigorous washing of the exposed surfaces. Possibly the perfusant injected into the circulatory system would leak out rather than get where it belonged if the skull was open. Or perhaps the ambient arterial pressure would tend to close up the veinous ends of the brain capillaries. Or perhaps things would shift around too much when the pressure of the skull was removed. Or perhaps the upside benefits are insignificant. Personally, I would rather keep a few more memories than an intact skull; I am already signed up neuro so they won't compromise my brain suspension trying to save my body. My uncle survived 25 years with a steel plate (installed at Corregidor) in his head. I suspect skull removal in surgery has got to be more benign than skull removal via Japanese bullet... Keith ? -- Keith Lofstrom Voice (503)-520-1993 KLIC --- Keith Lofstrom Integrated Circuits --- "Your Ideas in Silicon" Design Contracting in Bipolar and CMOS - Analog, Digital, and Power ICs Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=1429