X-Message-Number: 15346 From: Date: Mon, 15 Jan 2001 12:17:04 EST Subject: Wakfer 2 Referring now to Wakfer's #15340, taking issue with some of my statements in #15222: 1. Wakfer quotes part of what I said about toxicity and the K/Na ratio. Then he goes on with a long explanation of the K/Na ratio and its relevance. Nothing wrong with that, but I fail to see in it anything contradicting anything I said. What is interesting here, however, is that--contrary to what Greg Fahy said in the HSCP announcement--Wakfer says that 53% viability is a global assessment, NOT applying to individual cells. My original discussion of toxicity of the current Alcor procedure assumed just that--that the 53% was global or average, not necessarily applying to every individual cell. But then I was told that this was wrong, on the authority of an anonymous scientist, and later Greg said in the announcement published by Wakfer that this was wrong, and the 53% (now 66%) does indeed apply to each and every cell. I then responded mildly that Greg no doubt had some basis for his statement, although it seemed very queer from the standpoint of statistics, since in just about any population of any kind the variance is significant. If Greg has some way to assess the cells individually, no doubt we will hear the details eventually. So as far as I can see, this whole first segment of Wakfer's post said nothing to contradict me, and in fact supported me in an opinion previously disputed. 2. I had noted that a 21CM patent bore the names of people with little or no previous experience or publications in cryobiology, including Wowk, Federowicz, and Harris--and that this was encouraging. This was a compliment to the 21CM people, not a derogation. Part of Wakfer's response was: "2. Since when are the worth of scientific contributions to be judged by the worth or academic credentials of the contributor?" Hey, that's MY point, not Wakfer's. It is Wakfer and Platt and their ilk who (when it suits their purpose) emphasize the question of credentials. All right, actually, we all tend to do it to some extent. Certainly on our web site, with extensive quotations from Fahy, we emphasize his outstanding credentials. Certainly I will point out good credentials when it helps me. But I will NOT deny, and NEVER HAVE denied, any point of fact or evidence on the basis of reputation or credentials. On this point, I believe any neutral reader will give better marks to me than to Platt or Wakfer. 3. I had complimented the young (relatively young, if you want to quibble) 21CM people for advances not previously achieved by the whole cryobiology community. Wakfer now says the reason is that the community is small and has mainly not been interested in large tissue masses. First, this is denigrating the accomplishment, saying in effect that the achievement was significant only because previous efforts had been insignificant. It was I who acknowledged the talent, Wakfer who in effect deprecated it. Actually, attempts to freeze or vitrify whole organs have NOT been lacking, except perhaps in proportion to the importance of the possible result. There are hundreds of papers on whole organ work, going back almost to the earliest days. Fahy himself and colleagues have been at it for decades--yet the glycol ether "break-through" did not come from established cryobiologists, including Fahy's team, but from the few and relatively young and relatively uncredentialed people on the 21CM team. If Wakfer wants to try again, I don't mind at all. Nothing like a fight to draw a crowd. Whenever I am right, it will help cryonics, help CI, and tend to save lives. If I am wrong sometimes, which is a theoretical possibility, then we'll all learn something. Robert Ettinger Cryonics Institute Immortalist Society http://www.cryonics.org Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=15346