X-Message-Number: 1754 Newsgroups: sci.bio,sci.cryonics From: (Nick Szabo) Subject: Re: Aging Message-ID: <> References: <> Date: Tue, 16 Feb 1993 11:25:58 GMT N.B.: recently an RFD was posted for sci.bio.life-extension with positive response in news.groups. However, we need somebody who can receive and count votes. Any volunteers? (Gerard Mahalak) writes: > I am a biochemist and I am interested in aging theories. The wear and tear >theory, Hayflick limit, genetic clock, anti oxident theory. I have been >following the subject for a long time. Great, I'm also quite interested in this and would like to hear more of your ideas. The Hayflick limit (beyond which cells stop proliferating) is intriguing, because cell proliferation is a double-edged sword: it is needed to repair wounds and replace dead cells, but it can also turn into cancer. The aging body may walk a fine line between would-healing and carcinogenesis, and as the DNA becomes more damaged it becomes impossible to heal without proliferation running amok. Secondarily, the damaged DNA also produces more and more bad protein. If accumulating DNA damage is thus the underlying cause, what might slow down such damage? Antioxidants seem too non-specific, what about agents that act directly with DNA error correction? -- Nick Szabo [ FYI: Message #0020.6 is the 2nd RFD for the proposed USENET life-extension news group. The proposed name now is "sci.life-extension" rather than "sci.bio.life-extension". - KQB ] Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=1754