X-Message-Number: 19969 Date: Mon, 2 Sep 2002 13:25:41 -0700 (PDT) From: Doug Skrecky <> Subject: addendum to Thomas Donaldson Message #19959 From: Thomas Donaldson <> >Some time ago I wrote a book, A GUIDE TO ANTIAGING DRUGS, ... >criteria are basically simple: it must be shown to prolong the lifespan' >of some healthy strain of mammal. I do not accept work with flies, >worms, or clearly unhealthy animals. > After working with flies for some time, I have to agree with Thomas. If anything I am more conservative, and regard that the only true measure of man ['s longevity] is man. Published longevity research needs to be taken in context, to be understood. From the human context drosophila melanogaster flies are an animal model not of human "aging", but of Huntington's disease. Similarly C57B6J mice are not a good model of human "aging" either, but do serve as a good animal model for lymphoma cancer. IMHO, human "aging" itself is too general a term to be very useful. There do occur a variety of age associated ills in humans, but these pretty much have to be specified (such as sarcopenia) before intelligent comments can be made. Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=19969