X-Message-Number: 19983
From: Rafal Smigrodzki <>
Subject: RE: CryoNet #19979 - #19981
Date: Wed, 4 Sep 2002 09:11:02 -0400

"Basie" <> wrote:

One should not believe everything the drug companies tell you.  Maybe
statins do prevent some heart attacks. The question I would like them to
answer clearly is whether the life span of the average person that uses
statins is longer or shorter  over a period of thirty years.

### The effect of statins on the secondary and primary prevention of heart
attacks has been shown beyond reasonable doubt (a number of well-designed,
double-blind studies, evidence type A). Prolongation of life-span has been
also shown in some of the studies, as a secondary endpoint, definitely for
persons with 2 or more cardiac risk factors (evidence type A, if I remember
correctly), however, the evidence for persons without cardiac risk factors
is less strong (type B or C).

Rafal Smigrodzki, MD-PhD

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