X-Message-Number: 20136
Date: Sun, 22 Sep 2002 11:18:57 -0700 (PDT)
From: Doug Skrecky <>
Subject: 68'th update on fly longevity experiments

    This is the 68'th update of my fly longevity experiments. Average
temperature was 23.6 C during this run. Choline and vitamin B12 share a
synergistic action in stimulating brain acetylcholine, so here I team
CDP-choline and methycobalamin to see what happens. Synephrine has been
recommended as a relatively non-toxic alternative to ephedrine for weight
loss. I've tested both before in separate runs, but here I pit both head
to head in the same run.
    Methylcobalamin turned out to be a dud, but CDP-choline by itself
provided the best longevity results overall. Initially both doses of
ephedrine, and the high dose of synephrine performed worse than control,
but late in the run ephedrine, and low dose synephrine beat the control
survival.
    Eventually I'll have something more to report on CDP-choline, but for
the next run I take another look at cinnamon and paprika.

Run #68                        Percent Survival on Day
supplement                    9 16 22 29 37 46 55 64 75
_______________________________________________________
control                      81 63 56 44 21 19  0  -  -
apple pie spice 1/8 tsp      65 52 35  9  0  -  -  -  -
CDP-choline 250 mg           79 63 63 58 42 26 11  0  -
 +methylcobalamin 5 mg       86 76 67 43 10  0  -  -  -
charcoal steak spice 1/8 tsp 79 63 53 37 16  5  0  -  -
ephedrine 12 mg              79 67 61 52 36  6  3  0  -
ephedrine 48 mg              63 59 50 47 34 17 13  3  0
methylcobalamin 1 mg         79 67 67 33  8  0  -  -  -
methylcobalamin 5 mg         72 63 50 22  6  3  0  -  -
synephrine 14 mg             83 69 53 50 33  6  0  -  -
synephrine 54 mg             60 48 44 28 12  4  0  -  -

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