X-Message-Number: 20283
From: 
Date: Fri, 11 Oct 2002 09:50:16 EDT
Subject: Re: CryoNet #20276 Letter to New Scientist

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From: From Ralph Scurlock in a John deRivaz message:

> 
> The difference between successful cryopreservation and failure lies with
> size and achievable cooling rates. A single cell survives freezing if it
> cools so last that the entire cell freezes at once. Such cooling must take
> place at around 1000C per minute, even when using cryoprotectants.
> 
> If cooling takes place more slowly, the water in the cell freezes first and
> the consequent rise in concentration of dissolved substances within the 
> cell
> kills it, with no hope of later revival. Only thin sheets of human tissue,
> and single cells, can be cooled fast. enough.
> 

I agree with the above statements, it would be foolish to discard them. My 
conclusions are somewhat different from the ones of Mr. Ralph Scurlock:

1/ For current cryonics, I think the only way out is using uploading with a 
molecular brain reader. I have said that many times and I don't add more 
here.

2/ I think we have the think about a second generation cryonics:  Antifreezes 
are too far away from the aim to give a safe road to full body 
cryopreservation. There are two options:

2a/ A classical one using antifreeze, clay protection inside the cell, ATP, 
heat shock protein complexes,...

2b/ An advanced supercooling process similar to the Ulam thermonuclear setup 
where out of thermodynamics equilibrium compression allows to cool nuclear 
spins in nanoseconds. Here, the thermal sink could be some form of the zero 
point energy of vacuum, for example a non-separable Hilbert's space. It could 
be built as a mathematical ring above an additive group defined on a 
(classical separable) Hilbert's quantum space. Such a "seed" structure would 
look fractal in some range, pumping energy in it could exploit Regge's 
trajectory and produce a large principal quantum number object with 
macroscopic extension.

I understand that such concepts are somewhat contrived and well outside 
biologist minds. The technology may be deceptively simple yet, down to 
amateur level !(Think of that: it would freeze nuclear spins too and  produce 
a garage grade thermonuclear device :-).

Yvan Bozzonetti.


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