X-Message-Number: 22472 Date: Fri, 5 Sep 2003 21:39:40 -0700 (PDT) From: Doug Skrecky <> Subject: 102'nd update on fly longevity experiments This is the 102'nd update of my fly longevity experiments. Average temperature was 23.3 C during this run. Estimated maximal longevity using the formula (363 - T*11.2) is 102 days. Starting with this run, dark storage conditions are standard. Here I reexamine at higher doses oxymol, and sour cherry syrups, as well as take a first look at raspberry syrup. Oxymol has previously improved survival at a 2 teaspoon dose in run #98, and sour cherry was beneficial at 1 tsp in run #93. Oxymol this time yielded only a modest advantage at a 2 tsp dose, late in the experiment. Higher doses proved to be toxic. Sour cherry was also helpful at a 2 tsp dose, but 4 tsp was toxic. Raspberry was also slightly beneficial at the lower doses. In all these cases there appears to be a narrow therapeutic range, with effective doses becoming rapidly toxic at higher doses. [However the remaining raspberry syrup did prove to be delicious.] Starting with the next run I'll be testing the effect of raw vegetable extracts found at local supermarkets. Run #102 Percent Survival on Day supplement 5 10 15 21 26 31 38 44 49 54 60 66 ________________________________________________________________ control one 100 100 92 92 92 77 62 15 0 - - - control two 94 94 94 69 69 63 31 19 19 6 6 0 oxymol 2 tsp 100 92 92 83 75 67 50 38 33 17 0 - oxymol 4 tsp 96 87 87 83 78 70 39 4 0 - - - oxymol 6 tsp 94 94 88 69 63 50 13 0 - - - - raspberry syrup 2 tsp 100 95 95 90 90 71 57 33 24 5 0 - raspberry syrup 4 tsp 100 100 96 96 91 91 57 30 17 0 - - raspberry syrup 6 tsp 100 100 100 94 89 44 6 0 - - - - sour cherry syrup 2 tsp 100 95 95 95 95 89 63 53 21 11 0 - sour cherry 4 tsp 100 100 100 100 95 84 32 5 5 0 - - Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=22472