X-Message-Number: 23366
Date: Mon, 2 Feb 2004 20:03:44 -0800 (PST)
From: Doug Skrecky <>
Subject: 123'rd update on fly longevity experiments
This is the 123'rd update of my fly longevity experiments. Average
temperature was 22.1 C during this run. Estimated maximal longevity using
the formula (363 - T*11.2) is 116 days.
In run #121 white kidney bean appeared to offer some benefit during
the first few weeks of that experiment. This could have been a chance
finding. However the present experiment indicates that it was probably a
real, though transient beneficial effect of white kidney beans. Red kidney
beans offered no benefit in run #120.
In an as yet unpublished experiment, Tatar indicates that resveratrol
can increase maximum lifespan in drosophila. I had earlier tried
resveratrol myself, with null results. Since resveratrol is a very
unstable molecule, perhaps this result could have been expected. By
contrast, the resveratrol in dried peanuts is known to remain stable for
years. Some rather hydrophobic peanut skin was mixed in with wet fly food,
to further test resveratrol.
As expected, resveratrol itself was inactive. Although the highest
dosage of peanut skin did increase maximum lifespan from 71 to 98 days,
this is still less than the estimated maximal longevity of 116 days.
Possibly higher dosages of peanut skin might prove to be more beneficial,
particularly if it was first reduced to a fine powder. High doses of
peanut skin are being tested in run #132 to settle this matter.
Run #123 Percent Survival on Day
supplement 9 14 20 26 32 38 45 50 55 60 65 71 77 86 98 109
______________________________________________________________________
control one 80 80 80 75 75 60 40 40 20 15 15 0 - - - -
control two 91 91 86 76 62 48 48 43 19 14 10 5 0 - - -
kidney, white 8% 100 100 67 67 44 39 28 28 6 6 6 6 6 0 - -
kidney, white 33% 95 95 86 67 48 38 24 19 19 19 10 0 - - - -
peanut skin 1/4 tsp 98 73 63 58 50 40 28 15 8 5 3 3 3 0 - -
peanut skin 1/2 tsp 89 80 72 63 61 46 41 35 26 11 2 2 0 - - -
peanut skin 1 tsp 97 76 61 61 47 37 32 29 18 13 8 3 3 0 - -
peanut skin 2 tsp 95 79 64 52 50 43 43 36 31 26 24 19 10 2 2 0
resveratrol 100 mg 80 72 72 76 44 44 28 24 16 12 8 4 4 0 - -
resveratrol 200 mg 94 87 84 77 74 58 39 16 13 10 3 0 - - - -
resveratrol 400 mg 79 66 59 59 48 35 14 14 14 10 10 7 3 0 - -
resveratrol 800 mg 80 64 56 44 44 28 12 12 12 8 4 0 - - - -
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