X-Message-Number: 23418
Date: Tue, 10 Feb 2004 22:37:09 -0800 (PST)
From: Doug Skrecky <>
Subject: 124'th update on fly longevity experiments
This is the 124'th update of my fly longevity experiments. Average
temperature was 21.5 C during this run. Estimated maximal longevity using
the formula (363 - T*11.2) is 122 days.
Here I retest carob,and also give cocoa, and black grapes a try.
Rooibos tea has been a disappointment in the past, but here I try the
rooibos chips themselves, rather than just the hot water extract.
Once again carob offered a modest benefit, while cocoa turned out to
be inactive. Resveratrol rich grape peel offered nothing, while the pulp
was slightly useful, possibly by providing a little additional acid.
Rooibos was again a disappointment.
By chance one fly in the low dose grape pulp, and one in the rooibos
1/2 tsp bottle lived to an impressive 115 days, which is quite close to
the estimated maximal longevity of 122 days. In all of my previous
experiments only one fly fed some pomegranate paste in run #87 lived
longer - 124 days. However the average temperature was only 20.0 C for
that run, and estimated maximal longevity would then be calculated as 139
days.
Maximal longevity in drosophila has been determined to be controlled
by temperature dependant motor neuron degeneration. If my experiments do
turn up anything that could block this degeneration, then this might be of
value to humans, who suffer from Huntington's disease. If similar
increases in maximal longevity were subsequently to be found in other
short-lived animal species, then this might then be of some interest to
gerontologists, as well as life-extensionists.
Run #124 Percent Survival on Day
supplement 30 37 42 47 52 57 63 69 78 90 101 110 115 122
_____________________________________________________________________
control one 76 66 62 38 31 24 17 14 7 0 - - - -
control two 66 63 46 34 34 24 22 17 7 0 - - - -
cocoa 1 tsp 63 56 50 44 25 19 13 6 6 0 - - - -
cocoa 2 tsp 74 70 48 39 39 22 22 9 9 4 0 - - -
carob 1 tsp 72 62 62 55 52 55 45 28 24 10 0 - - -
carob 2 tsp 85 65 62 54 35 31 31 19 8 8 0 - - -
grape,blk,peel 1/4 tsp 91 76 61 52 39 36 30 18 9 6 0 - - -
grape,blk,peel 1/2 tsp 79 58 55 37 34 26 13 0 - - - - - -
grape,blk,peel 1 tsp 78 70 67 48 19 19 4 4 0 - - - - -
grape,blk,peel 2 tsp 65 52 35 52 35 26 17 9 4 0 - - - -
grape,black,pulp 8% 80 69 57 49 37 34 26 17 11 9 3 3 3 0
grape,black,pulp 33% 87 77 63 57 50 40 33 30 13 7 0 - - -
rooibos chips 1/4 tsp 65 65 44 38 27 24 21 18 3 3 0 - - -
rooibos chips 1/2 tsp 67 58 50 42 38 29 29 21 13 8 4 4 4 0
rooibos chips 1 tsp 61 26 26 26 26 13 13 4 0 - - - - -
rooibos chips 2 tsp 72 72 59 55 55 31 28 17 0 - - - - -
Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=23418