X-Message-Number: 23704 Date: Sun, 21 Mar 2004 20:49:39 -0800 (PST) From: Doug Skrecky <> Subject: 130'th update on fly longevity experiments This is the 130'th update of my fly longevity experiments. Average temperature was 20.2 C during this run. Estimated maximal longevity using the formula (363 - T*11.2) is 137 days. Lipoic acid by itself was something of a disappointment previously. This time a rather more expensive R(+) isomer was tested. One is reminded ofthe saying "throwing good money after bad". Aspirin had provided contradictory results in published experiments. This difference had been attributed to the confounding effect of pathogens in an experiment where positive effects were detected. Since I regard pathogens as being a major factor in fly mortality in my own "homebrew" experiments, there seemed to be a possibility of aspirin might be helpful. The present results indicate that this may indeed be so, provided the dosage is low enough to avoid toxicity. Run #130 Percent Survival on Day supplement 6 12 18 27 39 50 59 64 71 80 91 100 ______________________________________________________________ control one 100 81 77 71 45 36 23 13 10 7 0 - control two 96 96 80 72 64 52 28 12 0 - - - artichoke,cooked 5% 98 81 81 68 56 34 15 12 2 0 - - artichoke,cooked 20% 100 78 63 53 41 28 19 19 6 3 3 0 artichoke powder 405 mg 100 90 81 66 66 54 29 15 10 2 0 - artichoke powder 1620 mg 97 91 81 63 56 38 31 13 13 13 6 0 aspirin 81 mg 92 83 81 70 70 62 57 40 34 17 2 0 aspirin 325 mg 77 50 8 4 0 - - - - - - - BHA 88 mg 98 88 79 50 38 19 5 2 2 0 - - BHA 350 mg 100 85 65 46 0 - - - - - - - ibuprofen 50 mg 100 94 81 75 66 56 28 25 19 6 3 0 ibuprofen 200 mg 97 90 84 81 74 68 52 26 13 3 3 0 kiwi 5% 96 83 79 75 67 58 38 38 33 17 0 - kiwi 20% 88 72 59 56 41 38 19 19 9 3 0 - R(+) lipoic acid 50 mg 96 91 82 82 77 64 46 27 18 5 0 - R(+) lipoic acid 200 mg 100 87 81 68 43 30 11 5 0 - - - Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=23704