X-Message-Number: 23704
Date: Sun, 21 Mar 2004 20:49:39 -0800 (PST)
From: Doug Skrecky <>
Subject: 130'th update on fly longevity experiments

    This is the 130'th update of my fly longevity experiments. Average
temperature was 20.2 C during this run. Estimated maximal longevity using
the formula (363 - T*11.2) is 137 days.
    Lipoic acid by itself was something of a disappointment previously.
This time a rather more expensive R(+) isomer was tested. One is reminded
ofthe saying "throwing good money after bad".
    Aspirin had provided contradictory results in published experiments.
This difference had been attributed to the confounding effect of pathogens
in an experiment where positive effects were detected. Since I regard
pathogens as being a major factor in fly mortality in my own "homebrew"
experiments, there seemed to be a possibility of aspirin might be helpful.
The present results indicate that this may indeed be so, provided the
dosage is low enough to avoid toxicity.

Run #130                          Percent Survival on Day
supplement                 6 12 18 27 39 50 59 64 71 80 91 100
______________________________________________________________
control one              100 81 77 71 45 36 23 13 10  7  0   -
control two               96 96 80 72 64 52 28 12  0  -  -   -
artichoke,cooked 5%       98 81 81 68 56 34 15 12  2  0  -   -
artichoke,cooked 20%     100 78 63 53 41 28 19 19  6  3  3   0
artichoke powder 405 mg  100 90 81 66 66 54 29 15 10  2  0   -
artichoke powder 1620 mg  97 91 81 63 56 38 31 13 13 13  6   0
aspirin 81 mg             92 83 81 70 70 62 57 40 34 17  2   0
aspirin 325 mg            77 50  8  4  0  -  -  -  -  -  -   -
BHA 88 mg                 98 88 79 50 38 19  5  2  2  0  -   -
BHA 350 mg               100 85 65 46  0  -  -  -  -  -  -   -
ibuprofen 50 mg          100 94 81 75 66 56 28 25 19  6  3   0
ibuprofen 200 mg          97 90 84 81 74 68 52 26 13  3  3   0
kiwi 5%                   96 83 79 75 67 58 38 38 33 17  0   -
kiwi 20%                  88 72 59 56 41 38 19 19  9  3  0   -
R(+) lipoic acid 50 mg    96 91 82 82 77 64 46 27 18  5  0   -
R(+) lipoic acid 200 mg  100 87 81 68 43 30 11  5  0  -  -   -

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