X-Message-Number: 24285 Date: Tue, 22 Jun 2004 05:19:07 -0700 (PDT) From: Doug Skrecky <> Subject: a better alternative to CR for aged humans? (Caloric restriction is ineffective in slowing aging in already old animals. However it appears that activated carbon may offer some longevity benefit, even as a late life intervention.) Biomater Artif Cells Artif Organs. 1989;17(3):341-51. Effect of enterosorption on animal lifespan. Experiments were performed on Wistar male rats, starting from the 28th month of age. The effect of dietary sorbent (non coated nitrogen-containing carbon administered as 10 day courses at 1 month intervals in dosage of 10 ml/kg) on lifespan and a number of biological indices were studied. Enterosorption resulted in the increase of mean and maximal lifespan by 43 and 34% respectively. Analysis of the effect of enterosorption on activity of microsomal enzymes, intensity of total RNA and protein biosynthesis, lipid metabolism, formation of free radicals etc. showed that it produced a positive influence on the functional state of the studied systems and increased the organism's adaptive capacities. Enterosorption was found to delay the rate of onset of age-related structural changes in the organs and tissues. Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=24285