X-Message-Number: 25602
Date: Fri, 21 Jan 2005 10:17:05 -0800 (PST)
From: Doug Skrecky <>
Subject: 163'rd update on fly longevity experiments

    This is the 163'rd update of my fly longevity experiments. Average
temperature was 21.9 C during this run. Estimated maximal longevity
using the formula (363 - T*11.2) is 118 days.
    Aspirin improved fly survival in one published experiment, but did
nothing in a  follow-up test. The difference was attributed to poor
pathogen control in the earlier experiment. In run #130 of my own
experiments 81 mg aspirin was beneficial, while a higher dosage proved
to be toxic. Here I look at more modest doses of aspirin.
    Again the 81 mg dosage was helpful, but no conclusions could be
drawn regarding lower dosages. Salix alba contains aspirin-like
substances, but provided no statistically significant benefit at the
dosages tested.
    However one fly fed salix alba did break the previous record
longevity of 129 days, set by marmite in run #134. Although this new
record may be little more than luck, run #176 is currently giving salix
alba a chance to prove it wasn't a one-fly wonder.

Run #163                     Percent Survival on Day
supplement         19 34 41 51 59 70 78 88 98 108 116 121 123 130 132
_____________________________________________________________________
control one       100 96 85 72 52 46 26 13  4   0   -   -   -   -   -
control two       100 65 53 25 14 10  4  0  -   -   -   -   -   -   -
aspirin 10 mg      95 86 74 62 41 21 10  2  0   -   -   -   -   -   -
   "    20 mg      93 70 63 44 36 22 12  2  2   2   0   -   -   -   -
   "    41 mg      93 59 52 34 23 11  9  5  2   0   -   -   -   -   -
   "    81 mg      93 81 71 61 61 59 31 24 17   7   2   2   0   -   -
(calcium-   50 mg  96 82 64 42 32 18 16  6  0   -   -   -   -   -   -
glucarate) 200 mg  92 79 69 56 39 23 15 10  4   4   0   -   -   -   -
marmite 1/2 tsp    98 86 71 52 33 12  0  -  -   -   -   -   -   -   -
   "    1/2 tsp    82 71 46 29 21 14  0  -  -   -   -   -   -   -   -
salix alba 50 mg   90 85 78 60 50 35 28 15  8   3   3   3   3   3   0
   "      100 mg  100 88 80 58 43 30 28 18  0   -   -   -   -   -   -
   "      200 mg   97 59 52 41 40 24  7  0  -   -   -   -   -   -   -
   "      400 mg   84 58 53 42 21  5  5  0  -   -   -   -   -   -   -

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