X-Message-Number: 26294 Date: Mon, 6 Jun 2005 22:29:51 -0700 (PDT) From: Doug Skrecky <> Subject: 177'th update on fly longevity experiments This is the 177'th update of my fly longevity experiments. Average temperature was 22.2 C during this run. Estimated maximal longevity using the formula (363 - T*11.2) is 115 days. In this run, I take another look at urea, which at an 1/8 tsp dose was associated with an increased average, but not maximal longevity in run #173. Lactoferrin is an iron chelator, and triphala is a potent superoxide scavenger. Lactoferrin turned out to be dud, but a couple of flies fed a high dose of triphala did outlive the controls, although this might still have been due to chance. Urea at the 1/8 tsp dose was helpful once again, and the 1/16 tsp dose appeared to be even better. Low doses of urea might be reducing mating frequency, and thereby improving average longevity by reducing exposure to mating associated mortality. Urea is being further examined in run #192, and if this benefit is further confirmed, low dose urea may become a standard additive in future to all fly runs. Run #177 Percent Survival on Day supplement 6 18 28 37 44 52 61 69 79 87 93 100 108 116 _______________________________________________________________ control one 96 74 57 57 57 52 49 26 13 9 4 0 - - control two 97 55 55 52 52 46 33 24 15 9 3 0 - - lactoferrin 63 mg 90 61 61 61 58 46 36 26 19 16 10 0 - - " 250 mg 100 68 64 59 50 27 9 5 5 5 0 - - - triphala 63 mg 97 74 65 59 56 44 24 15 6 3 0 - - - " 250 mg 100 65 62 62 57 51 41 27 27 16 8 5 3 0 urea 1/16 tsp 100 94 86 81 75 72 64 53 42 39 22 0 - - " 1/8 tsp 96 72 64 64 60 56 52 40 28 20 8 0 - - " 1/4 tsp 100 89 89 82 75 68 46 39 18 11 4 0 - - " 1/2 tsp 97 74 68 68 68 29 16 10 3 0 - - - - " 1 tsp 100 94 75 63 41 22 3 0 - - - - - - Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=26294