X-Message-Number: 26375 References: <> From: Kennita Watson <> Subject: Re: CryoNet #26365 - #26369 Date: Wed, 22 Jun 2005 14:21:21 -0700 Doug Skrecky wrote: > Cerium oxide nanoparticles turned out to be non-toxic to flies at > all > concentrations. However no effect on fly longevity was observed. I > have > to regard this as a refutation of the free radical theory of aging. > Playing the devil's advocate, this test of the free radical theory > of > aging could be criticized along the following lines. The particle size > may have been too large so mitochondrial penetration may have been as > issue. Possibly too high a concentration of nanoparticles was used. > Also, the cells tested in vitro were brain cells. Maybe the fly food nanoparticles couldn't make it across the blood-brain barrier -- and might not in live rats, either. Kennita Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=26375