X-Message-Number: 26767
Date: Thu, 4 Aug 2005 19:48:28 -0700 (PDT)
From: Doug Skrecky <>
Subject: 185'th update on fly longevity experiments
This is the 185'th update of my fly longevity experiments. Average
temperature was 23.9 C during this run. Estimated maximal longevity using
the formula (363 - T*11.2) is 95 days.
As part of a standard screening process, I like to check anything
that exerts neuroprotective effects in any animal species. Spirulina
algae has effectively blocked brain aging in Fisher 344 rats. (J
Neuroscience 22(14): 6114-6120) Hence here I test a variety of algae.
Alas, neither chlorella nor spirulina algae offered any benefit.
The middle (1/4 tsp) dose of blue-green algae appeared to offer some
benefit on average, but not maximum longevity. However this may have been
due to chance.
A wide variety of antioxident rich foods (apples, blueberrys,
spinach, spirulina, strawberrys) have slowed or even halted brain aging
according to various criteria in rodents. It is possible that this
may merely reflect how poor the control commercial rodent chow is. In any
case I have consistently found no longevity benefit for such foods when
they are mixed with 4-24 fly food.
Run #185 Percent Survival on Day
supplement 7 17 25 31 38 46 54 64 71 81 88
____________________________________________________
control one 86 86 76 76 71 52 43 29 14 5 0
control two 86 62 67 67 57 52 38 10 5 5 0
blue-green 1/16 tsp 96 72 60 56 56 52 40 28 8 0 -
"(algae) 1/4 tsp 96 83 78 78 74 70 65 52 30 13 0
" 1 tsp 83 72 61 61 56 44 33 17 11 0 -
chlorella 1/16 tsp 90 68 68 58 53 37 37 32 16 0 -
" 1/4 tsp 91 91 76 62 38 29 19 14 14 5 0
" 1 tsp 83 61 50 50 50 39 39 33 28 11 0
spirulina 1/16 tsp 77 46 54 46 46 31 23 23 15 0 -
" 1/4 tsp 96 83 61 44 39 30 26 17 4 0 -
" 1 tsp 77 53 47 47 24 24 18 18 6 0 -
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