X-Message-Number: 26881
Date: Thu, 25 Aug 2005 00:56:59 -0700 (PDT)
From: Doug Skrecky <>
Subject: 190'th update on fly longevity experiments

     This is the 190'th update of my fly longevity experiments. Average
 temperature was 25.4 C during this run. Estimated maximal longevity (EML)
 using the formula (363 - T*11.2) is 78 days.
     Recently a pomegranate juice from POM became available in Canada.
 This is a refrigerated, and hence fresher product than the
 (unrefrigerated) Kambiz pomegranate paste that I had used earlier. This
 run tests to see if freshness makes a difference in the longevity
 results.
     To my great surprise the answer to this question appears to be
 negative, at least at the lower dosages. Although pomegranate paste has
 repeatedly bested control longevity in the past, it had never come up
 against a control, which itself tested the limit set by EML. Although
 pomegranate at the appropriate dosages bested control two, it failed to
 beat control one. I interpret this as implying that pomegranate probably
 exerts no anti-aging effect as such, but instead can help reduce pathogen
 associated mortality, and so increase the likelyhood that some (fragile)
 flies can live to an extreme old age.

 Run #190                      Percent Survival on Day
 supplement                 13  23  30  40 47 56 66 76 83
 ________________________________________________________
 control one               100 100 100 100 80 40 20 20  0
 control two                83  75  58  42 33  8  0  -  -
 pomegranate juice 10%      62  39  46  23 15  8  0  -  -
   "               20%     100  70  60  60 50 20 10  0  -
   "               40%     100  90  80  70 70 50 30 10  0
   "              100%     100 100 100  86 57  0  -  -  -
 pomegranate paste 1/2 tsp 100 100 100  90 90 20  0  -  -
   "               1 tsp   100 100 100  88 63 38 25  0  -
   "               2 tsp   100 100  63  25 13  0  -  -  -
   "               4 tsp   100  83  50  50  0  -  -  -  -

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