X-Message-Number: 27002
Date: Sun, 11 Sep 2005 11:51:16 -0700 (PDT)
From: Doug Skrecky <>
Subject: 194'th update on fly longevity experiments

     This is the 194'th update of my fly longevity experiments. Average
 temperature was 25.8 C during this run. Estimated maximal longevity using
 the formula (363 - T*11.2) is 74 days.
     Lovastatin is a prescription only item. However it is also found in
 fermented red yeast rice extracts, which are available OTC, probably
 because they are a dilute source of lovastatin. Nonetheless red yeast
 rice by itself was recently banned in Canada, although it is available
 for the time being in combination products. One such combination still
 has a fairly hefty amount of red yeast rice, plus only minor additions of
 guggulipid and artichoke. Since previous testing indicated that neither
 of these additives was toxic to flies, I decided to try testing this red
 yeast rice product [by Organika).
     Alas, red yeast rice had no impact on fly survival at any dose. I
 interpret this to mean that lovastatin, and by extension all other
 statins at low doses would likely also have no effect on fly survival. On
 the plus side, it does appear that this red yeast rice product is
 completely non-toxic.

 Run #194              Percent Survival on Day
 supplement               14 21 30 40 50 57 64
 _____________________________________________
 control one              82 77 53 24 12  0  -
 control two              50 50 41 27  9  5  0
 bi yan pian 1 pill       77 77 59 12 18  0  -
   "         4 pills      85 80 50 35 25  5  0
 co-schisandra 1 pill     70 57 39  9  4  0  -
   "          4 pills     52 44 20  4  0  -  -
 red yeast rice 125 mg    66 59 50 28  9  0  -
   "            250 mg    61 61 48 26  4  0  -
   "            500 mg    55 40 30 20  5  0  -
   "           1000 mg    64 55 36 23  5  0  -
 fructus persica 1 pill   48 43 33 10  5  0  -
   "             4 pills  71 62 48 19 10  0  -
 trisnake 1 pill          56 50 50 28 28 11  0
   "      4 pills         62 57 33 24  0  -  -
 zhong gan ling 1 pill    53 53 29 12  0  -  -
   "            4 pills   57 52 44 17  9  0  -

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