X-Message-Number: 27363
Date: Tue, 15 Nov 2005 18:21:00 -0800 (PST)
From: Doug Skrecky <>
Subject: 203'rd update on fly longevity experiments

     This is the 203'rd update of my fly longevity experiments. Average
 temperature was 25.8 C during this run. Estimated maximal longevity using
 the formula (363 - T*11.2) is 75 days.
     B.R. donated a small amount of hydergine and bromocriptine for the
 current run. Hydergine was slightly toxic at high doses. Bromocriptine
 exhibited a weird inverse dose related toxicity where high doses were
 less injurious than low doses. I am at a loss to explain this peculiar
 result.

 Run #203                Percent Survival on Day
 supplement             6  12 18 24 32 41 51 61 68
 _________________________________________________
 control one          100 100 88 75 19 19 13  6  0
 control two          100  88 77 53 35 29 24  6  0
 hydergine 0.56 mg    100  83 54 33 25 13 13  4  0
   "       1.1 mg     100  71 59 47 24  6  0  -  -
   "       2.3 mg      95  74 58 32 21 11  0  -  -
   "       4.5 mg     100  69 54 54 31 15  0  -  -
 bromocriptine 0.6 mg 100 100 75 60 35 10  0  -  -
   "           1.3 mg 100  80 65 40 20  5  0  -  -
   "           2.5 mg  95  79 68 53 37 16  5  0  -
   "           5 mg   100  71 52 43 24 14 10  5  0

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