X-Message-Number: 27368
Date: Thu, 17 Nov 2005 19:16:44 -0800
From: Olaf Henny <>
Subject: Solvents to facilitate perfusion?
References: <>

Has anybody ever thought of exploring the employment of the membrane 
permeating abilities of the solvent DMSO (dimethyl sulfoxide) or its 
derivative MSM (methylsulfonylmethane) to get vitrifying agents to perfuse 
the brain tissue or any other tissue for that matter?
As both agents are approved for medical use in several counties, including 
Canada, where Pennsaid, which uses MSM as solvent, was approved as 

topical treatment in clinical trials for osteoarthritis, they are not very 
to cause much tissue damage.

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