X-Message-Number: 28700 Date: Thu, 30 Nov 2006 02:07:26 -0800 From: Edgar Swank <> Subject: Comment on gas hydrate perfusion. In CryoMessage #28697, Yuriy Pichugin is sceptical about results claimed for gas clathrates. But this is similar to an idea I have had for a long time and would like to see explored, gas perfusion in general. If a gas can be used to perfuse to below the freezing point of water, and possibly even to just above LN2 (using N2), then cells can be cooled both rapidly and evenly, because the circulatory system has individual access to every cell in the body. Fast and even rewarming can also be accomplished if the circulatory system remains open in the cryopreserved state. Since individual cells can be frozen, kept frozen, and rewarmed to life now, cryopresrvation of whole organs or entire bodies would seem to be solved. I expect the problem is to somehow displace all the liquid in the circulatory system because it is massively parallel and gas under pressure could find a path around and leave a lot of liquid there. Possible solution to explore could include use of both pressure and suction, and varying ambient pressure either up or down. -- Edgar W. Swank <> Home Page:http://members.fortunecity.com/edgarswank Phone: 408-227-3471 Cell: 408-605-4721 FAX: 810-277-7274 Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=28700