X-Message-Number: 28723 Date: Wed, 6 Dec 2006 11:52:34 -0800 (PST) From: Subject: 232'nd update on fly longevity experiments This is the 232'nd update of my fly longevity experiments. Average temperature was 25.2 C during this run. Estimated maximal longevity using the formula (363 - T*11.2) is 81 days. This run retests grape seed leucoanthocyandins, which previously showed some advantage in runs #22 & 29. A tumor necrosis factor alpha inhibitor called oxpentfylline, and a new pomegranate seed product both get the fly longevity test. Tumor necrosis factor alpha is believed to be a driving factor in human centenarian mortality. None of these products offered any advantage in this run, with pomegranate seed being somewhat toxic at very high dosages. Run #232 Percent Survival on Day supplement 7 21 35 51 62 77 ___________________________________________ control one 87 67 9 2 0 - control two 85 56 27 6 3 0 leucoanthocyandins 95 mg 86 73 26 7 2 0 " 380 mg 85 59 21 3 0 - oxpentfylline 25 mg 91 68 19 6 4 0 " 50 mg 87 63 32 11 3 0 " 100 mg 79 51 18 3 0 - " 200 mg 73 47 13 5 0 - pomegranate (seed) 125 mg 82 61 11 5 0 - " 250 mg 84 47 4 4 0 - " 500 mg 57 48 9 0 - - " 1000 mg 56 11 7 0 - - Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=28723