X-Message-Number: 30843
From: "Chris Manning" <>
References: <>
Subject: Re: Reversal of aging by NFkappaB blockade
Date: Fri, 4 Jul 2008 01:32:13 +1000

----- Original Message ----- 
From: "CryoNet" <>
To: <>
Sent: Tuesday, July 01, 2008 7:00 PM
Subject: CryoNet #30838 - #30840


> Message #30840
> Date: Mon, 30 Jun 2008 10:24:54 -0700 (PDT)
> From: 
> Subject: Reversal of aging by NFkappaB blockade

[various snips]

> Abnormal expression of cyclooxygenase-2 (COX-2) has been implicated in
> the development of cancer. There are multiple lines of evidence that red
> wine exerts chemopreventive effects, and 3,5,4'-trihydroxy- trans-stilbene

........

> P+ cells. Collectively, these data suggest that myricetin contributes
> to the chemopreventive effects of red wine through inhibition of COX-2
> expression by blocking the activation of NF-kappaB.

I would be glad to know which of the statements about red wine above are 
also true of grape juice.

> Inhibition of cancer cell proliferation and suppression of TNF-induced
> activation of NFkappaB by edible berry juice.
> Boivin D, Blanchette M, Barrette S, Moghrabi A, B liveau R. Laboratoire
> de M decine Mol culaire, H pital Ste-Justine-UQAM, Centre de Canc rologie
> Charles-Bruneau, Centre de Recherche de l'H pital Sainte-Justine, 3175,
> Chemin C te-Sainte-Catherine, Montr al, Qu bec, Canada.

I wish the webmaster would do something about this problem of accented 
letters.

See how much more readable the above becomes when I insert the missing 
letters (without their accent marks, obviously):

> Boivin D, Blanchette M, Barrette S, Moghrabi A, B liveau R. Laboratoire
> de Medecine Moleculaire, Hopital Ste-Justine-UQAM, Centre de Cancerologie
> Charles-Bruneau, Centre de Recherche de l'Hopital Sainte-Justine, 3175,
> Chemin Cote-Sainte-Catherine, Montreal, Quebec, Canada.

(A French dictionary supplied the word 'cancerologie' and a Google maps 
search provided the name of the street. I'm not sure about the surname, 
although the missing letter is obviously a vowel.)

The growth of various cancer
> cell lines, including those of stomach, prostate, intestine and breast, 
> was
> strongly inhibited by raspberry, black currant, white currant, gooseberry,
> velvet leaf blueberry, low-bush blueberry, sea buckthorn and cranberry
> juice, but not (or only slightly) by strawberry, high-bush blueberry,
> serviceberry, red currant, or blackberry juice.

I tried to find raspberry, blackcurrant gooseberry or cranberry juice in my 
local supermarket.

There are plenty of items called 'fruit drink' or 'fruit juice drink' which 
are typically 25% fruit juice and contain added sugar. It would be a pity if 
the benefit obtained from the juice were counterbalanced by harm from 
consumption of excess sugar. I found several brands of something called 
'apple and blackcurrant juice' but if you read the label, they are always at 
least 95% apple juice and at most 5% blackcurrant juice. Of course you could 
drink a large amount of these just for the blackcurrant juice content but I 
gather that even without added sugar it is possible to get too much sugar 
just by drinking a lot of fruit juice. I settled on something called Ocean 
Spray Cranberry Classic, which the label says contains 25% fruit juice and 
(of course) added sugar. I will try to find something better somewhere else 
but that will do for now.

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