X-Message-Number: 33398 References: <> From: Gerald Monroe <> Date: Mon, 28 Feb 2011 12:21:47 -0600 Subject: Re: CryoNet #33363 - #33394 --20cf307f389ac0072a049d5bc92f Robert Ettinger - why do you consider uploading to be nonsense? To reverse current suspensions, the most comprehensive and logical solution is an atom by atom scan of every fragment of the frozen brains in the dewars today. Current methods and equipment don't have anywhere near atomic level resolution - if we scanned a brain today, we'd destroy a portion of it making the slices, and would scan each slice using a relatively low resolution light microscope. If you are wondering what I am talking about, here's a website where a brain was scanned using today's methods : http://thebrainobservatory.ucsd.edu/hm_live.php From this scan, we can probably determine some of the reasons why the patient was unable to form new long term memories. If we knew what to look for, we might be able to infer a rough guess of the patient's personality and temperment, as well as what types of things the patient was skilled at. But nothing specific enough that the patient would experience continuity of existence, which is the primary ultimate goal of cyronics. However, atomically precise scans are theoretically possible, and we can do them today for small two dimensional surfaces. Anyways, once we perform such a scan, we'll know exactly with almost perfect resolution the physical structures of the synapses of the brain. Currently, we think that all information stored in the brain is represented by interactions between networks of synapses that each have a potential for firing and potentials for changing, aka thresholds and plasticity. Some areas of the brain are far more plastic than others, and can actually form new synapses - although we currently think that new synapses are formed randomly, and they are retained or deleted depending on how useful a new connection is. In any case, all of the biology - all of the ridiculous complexity - is most likely reducable to a simpler set of rules that apply per synapse. At any given connection in the brain, there might be 10 or less parameters that represent the "state" of that location. A parameter for the density for each protein type related to the handling of charge and neurotransmitters, for the concentratration of loose long distance neurotransmitters that bathe the intracellular fluid, and so on. Anyways, once we map someone's mind, what do we do next? Neuroscientists of the future will have to understand exactly what they are doing to even attempt a revival. While we do not know all of the precise details of how the brain's interconnects actually work today, that will have to be known by the time a revival is even contemplated. Well, the most logical step is to take the exact same technology we used to make the molecular scan - molecular manufacturing - and print ourselves a massive cube of electronic circuitry that precisely emulates each and every synapse of the cryonic patient's mind. Since each and every processing core is a copy of every other one (just loaded with different data reflecting the current state of a synapse) and following the same microcode, human beings could engineer and build such an emulator. Also, when things go wrong, we can debug something that we designed and created. It's possible that the brain exploits strange quantum effects that conventional digital circuitry can't reproduce. Not a problem - just add molecular circuits to our cube that emulate this property of the brain as well. As long as you assume that the brain relies on matter and energy to perform computation, and that alternate designs of a brain could run the same human personality, then this is ultimately possible. Also, actual studies of real neural tissue reveal the stuff is horribly noisy and unreliable and so many of the subtle effects we wonder about are likely lost in the noise. Or, door number 2 is we attempt to use our molecular manufacturing to create a new brain, with each neuron and glial cell and blood vessel and everything else made from a molecular pattern representing a *living *state. Also, the manufacturing equipment will have to work with a solid, so the living neurons must start as frozen and be constructed to survive thawing. I think this is possible, but the complexity - understanding of living systems to the level of God himself - may be beyond the capabilities of human brains to ever solve. I firmly believe revivals can be done with a person waking up in the peak of health, but it'll probably take a hybrid approach such as first opening door #1, bringing people back as emulations of their formal selves, and running those emulations at speeds millions of times faster than realtime to solve the problems with approach number 2. In any case, please pop my soap bubble. What facts and data can you bear to show that we can't emulate a system that was apparently designed through pure blind chance and is a prototype in the natural world. (humans are basically prototypes because we haven't existed for enough generations for evolution to refine us, which is both why our brains can fail so spectacularly and why no other species has our capabilities) I don't mind learning that I am wrong. I took my first neurscience course in medical school fairly recently. It's just that there's an awful lot of stuff I've learned about that support this idea. Gerald Monroe p.s. : Rudi : this is why computer scientists were the first to jump on cryonics. It takes a deep understanding of math to visualize a software function with 10+ variables representing each synapse, and how trillions of said functions interacting together could lead to the emergent complexity we actually see in humans. And that a copy is as good as the original, and that exponentially more intelligent systems are possible. Most people in the United States probably ultimately believe that our God given souls trigger each neuron like strings on a puppet. --20cf307f389ac0072a049d5bc92f Content-Type: text/html; charset=ISO-8859-1 [ AUTOMATICALLY SKIPPING HTML ENCODING! ] Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=33398