X-Message-Number: 4294 From: (Thomas Donaldson) Subject: Re: CryoNet #4280 - #4287 Date: Tue, 25 Apr 1995 23:59:07 -0700 (PDT) Hi again! Several questions and comments: Yes, if leeches do the right thing on injury the suggestion of experimenting on freezing them would be a very good one. The interesting fact about salamanders is that they have a much greater ability to repair their brains after severe injury than any mammal. That is why I mentioned them specifically. Any animal with a LOT of repair capability for its nervous system would tell us something about the effects of freezing on human beings. (In more detail, I'd say this: micrographs of tissue after freezing show a lot of damage. At the same time, some animals have far more ability to repair themselves than we do. If they could repair themselves even partially after freezing, that would tell us that if we could unblock our own repair ability (in terms of nervous system repair, there seem to be some chemicals we make which tend to block it, it's not the same as having no repair ability at all) the repair task might not be as great as it seems from looking at the damaged nervous tissue). It would be of interest to learn, for instance, whether salamander nerve cells survive freezing and how well they do so. Can they repair their own nerve connections?). I'm not familiar enough with leeches to know whether or not they have any such capability ... but perhaps they do. I'm happy to go into more detail, with references too, if it looks like you can do this experiment. As for improvements in memory: I would be very happy to find good ways to improve my memory, but the connection between memory and intelligence is not direct at all. Intelligence is a much harder notion, to start with... I'm not at all sure anyone has yet come up with a good definition, for instance. As a matter of fact, I'd also say that what we have learned about computers (I don't mean expensive ones) raises lots of questions about the nature of intelligence, and as we learn more about other animals we've sometimes found that they have specialized mental abilities greater than our own. Some birds store food for themselves in the winter, and remember precisely the exact locations where they put it (they don't store it all in one place). These come to thousands of locations. I'm not sure human beings can do that without the help of writing. About technological panaceas: I would agree that our situation is not the same as that of those who worked with rockets, such as von Braun. I doubt that many cryonicists believe that revival will NECESSARILY AND CERTAINLY happen. But that is not the point. We want to be frozen because the alternative is far worse, not because we think it will necessarily work. The fact that we all expect to be frozen AT DEATH (death is a complex notion, much more complex than you presently think) is crucial here. If you want to survive, it is foolish to choose an alternative such as cremation or burial which will clearly prevent your survival over an alternative such as cryopreservation which MAY keep you alive. And I say this, personally, as someone who has survived (so far) a brain tumor which kills 80% of those who get it. Most people who aren't cryonicists seem to evaluate cryonics as if it were some kind of trip to the Moon: fun, but not necessary. When they do that they miss the point entirely. And I will add that I got my brain tumor quite unexpectedly 15 years after I first signed up for suspension, and got insurance to pay for it because when I signed up I was in perfect health. And similarly, to understand this central point may help to understand such things as Brian Wowk's discussions of nanotechnology. There are reasons to believe that cryonics will actually work: not reasons in the sense of hard and fast promises, but reasons in the sense of intelligent speculation. And don't think that such speculations are out of the question: when you invest in anything (and it's almost impossible not to invest!) then you are making a speculation about the future. No one can prove to you that the house you buy to live in will go up in value, or even that the Treasury Bill you buy will pay off without being wiped out by inflation. All those things involve speculation on the future. And when it comes to a choice between total destruction and possible survival, a speculation on possible survival wins hands down. Finally, just as others have said, it's possible to work to improve our suspension methods, RIGHT NOW. And if anything that makes the speculation much better: if you can do something to help bring about the events which will lead to your survival (or, for comparison, your investment rising in price) rather than simply watch the market bobbing up and down, then you have a much better speculation than if you must depend completely on matters outside your control. These are comments I would add to those of Brian Wowk. Long long life, Thomas Donaldson Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=4294