X-Message-Number: 4659 From: Date: Fri, 21 Jul 1995 20:11:38 -0400 Subject: p.s. Adding to my previous post today, and responding to Mike Darwin's #4656: 1. For some readers, the main thrust of Mike's message will be his contention that patients suspended by recent (and not so recent) BPI or Alcor methods have a better chance of revival than patients suspended by CI methods. This is based mainly on interpretation of micrographs as showing better ultrastructure. However: a) Mike agrees that there are many unresolved difficulties in intrepreting these photos. b) CI sheep brains showed no cracking. Cracking may or may not be very important, but the CI results are the only ones to date clearly showing no cracking after rewarming from liquid nitrogen temperature. (I understand from Mike that he and Paul Wakfer are testing CI's cooling/warming protocol to see if that is the difference.) If cracking is very important, then--so far--possibly CI's patients have the better of it. (My own honest opinion is that cracking is probably not a major issue, but some others think differently, and we just don't know.) c) BPI or/and Alcor methods (at various stages of their development) may have or may have had other problems. For a while, when Mike was there, Alcor sometimes exposed its patients to alcohol, which they later admitted was a mistake (and a not inexpensive one!). Also, if I remember correctly, Alcor under Mike and Jerry Leaf for a while used DMSO; CI always used glycerol. There is also the admittedly unresolved problem of glycerol toxicity, which could cut either way; we just don't know yet. d) It is VERY possible that nanotech or equivalent will be both necessary and sufficient to rescue patients suspended by ANY of the methods heretofore used, and perhaps even by straight freezing as well. In that case, all patients have roughly equal chances, regardless of what they paid. 2. The more important question, from the point of view of prospective patients, is who will offer the best suspension and the best overall chances in the future--ten years hence or more for most readers. Speaking for Cryonics Institute, I repeat that we will offer those procedures confirmed best, either routinely or as a higher-priced option if necessary. The confirmation, and any changes, will probably be gradual and ongoing. If we (collectively) reach the Holy Grail of reversible-on-demand suspended animation in my first lifetime, we will certainly offer that. 3. How can individuals judge between various claims and interpretations? (a) They can follow their noses or impulses or loyalties, and this is what most will do. (b) Those so inclined can review the detailed history and indulge in some amateur psychoanalysis. (c) Those so inclined and qualified can review all the objective data and form their own opinions. (d) Those who can't afford more than $28,000 can choose CI as the only available alternative, whether or not they think it is also the best. (e) Those who can afford anything and believe the premium price necessarily reflects the best can choose the highest priced. 4. Who among spokesmen is likely to be most objective and least likely to be self-serving? The virtue of which I am proudest is my humility; I may not be totally free of vanity or jealousy, but these have steadily diminished along with my life expectancy. Also, having lived longer, I have probably made more mistakes than other spokesmen. As Tevye said about being poor, making mistakes is no disgrace but it's no great honor either--yet it does tend to vitiate vanity, unless you are psychopathic. I might also gently point out, for whatever it is worth, that CI (along with Alcor and ACS) is nonprofit; and CI's officers and directors, including myself, get no pay or any kind of financial benefit. People working for pay or profit can certainly be honest--but it is just a wee bit harder, and it becomes easier to fool yourself. CryCare is also nonprofit, but its preferred service providers are for-profit. 5. CI has what the unfriendly might call a small element of "communism" in it, in that some voluntarily fund at higher levels, or/and leave CI their estates, with no guarantee of corresponding benefits (although they do get priority consideration in some circumstances). CryoCare uses completely separate individual trusts, so a CryoCare member who falls a nickel short is out of luck, at least theoretically, as I understand it. Alcor is in between, with some older members grandfathered in at lower prices than newer members; and many Alcor people have made donations of various kinds. Now, Mike favors the CryoCare approach, which some think is more in line with Libertarian ideas. However: (a) CI has a fair number of Libertarians. (b) CI members may, if they wish, fund their suspensions at the CI minimum and set aside separate trusts for themselves. They can even use CryoCare and BPI, and use CI for storage. (c) Ideology can be very misleading, as always. When Mike was at Alcor, he defended Alcor's "College of Cardinals" (a ruling Board that chose its own successors) in part by noting the success of the Roman Catholic Church. He conveniently forgot many other salient features of the Church, such as vows of poverty and obedience, commitment to charity, etc., not to mention dogma and deity. If we are looking for models ( a mostly futile endeavor), what about the FAMILY? There's a pretty enduring institution for you. Do families demand a penny-for-penny accounting from each member, or do they make adjustments based both on narrow individual self-interest and on broader self-interest that seeks the advantage of the whole family? Many of us tend to think of Cryonics Institute as a family. It certainly isn't just another business. Mae and I have prepaid our suspension fees, and in addition, after we both die, CI will get the bulk of our estate. We don't think that is foolish or that it will impair our chances--on the contrary. Again, forgive the rambling. I hope I can abstain for a while. Finally, Drs. Pichugin, Marchenko, and Shilo have sent us the tables of results and the first part of the report on spontaneous and evoked bioelectric activity in pieces of rabbit brain treated in various ways, including glycerolization and cooling to liquid nitrogen temperature. We will publish results in full in THE IMMORTALIST (probably September issue) and at least a summary on Cryonet. Robert Ettinger Cryonics Institute Immortalist Society Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=4659