X-Message-Number: 5760 From: Date: Mon, 19 Feb 1996 13:10:28 -0500 Subject: SCI. CRYONICS "impossible" repair Marshall Rice has posted various messages on the "impossibility" of reviving a person from "dead meat." John de Rivaz and others have provided some pretty good partial responses, and I should probably just ignore it, but I'll throw in a few bits worth and heroically restrain myself from using some colorful adjectives to characterize Mr. Rice's thought processes. 1. (Minor comment.) He uses the word "impossible" and also says he cannot "conceive" etc. I learned at a VERY early age that the limits of the possible and the limits of my ability to conceive are not the same. 2. On the theoretical/philosophical level he appears--shall we say--naive. He thinks he knows the defining features of self and consciousness and individuality, or their necessary and sufficient conditions, when in fact these things are unknown. (Granted, he isn't alone in thinking his opinions constitute fact.) He appears to be quite ignorant of the voluminous literature on criteria of identity or criteria of survival. 3. He thinks every neural pathway must be saved or repaired or reconstituted if the individual is to survive. But these pathways are constantly changing in the ordinary course of life, and unless he is prepared to argue that continuity can substitute for identity (an exceedingly weak argument), this criterion must be abandoned. 4. Further, when he speaks of "every neural pathway," he ignores or hasn't realized the fact that MOST neural pathways relate merely to "computational" features of the brain, and not to anything irreplaceable. 5. His analogy about progressively destroying books is inapt, but doesn't succeed anyway. The U.S. embassy in Iran used paper shredders to destroy records at the time of the Iranian revolution, but those crazies just sat down with the shreds and put them back together, and read our documents. Even charred and partly burned records have been reconstituted--and that with present or earlier technology. Many people give lip service to the potential of future technology, but few really mean it or understand that potential. 6. He wants to use "onset of cellular death" as the criterion of forever-impossible repair. He seems sometimes vaguely to concede that "destruction" and "death" are matters of degree, but in the next moment seems to forget it. "Death"--cellular or otherwise--is usually defined as "irreversible loss of vital functions," but of course reversibility is a question of time and technology, hence "death" is always a PROGNOSIS, not a diagnosis. 7. He says the onset of tissue death is usually three minutes after ischemia sets in. This is not true. Many experimental mammals, and several humans (going back at least to the 1970 work of Hossmann & Sato), have been revived after as much as an hour of ishemia and anoxia. His "usually" doesn't save him either, because there is abundant evidence that often, if not usually, the failure to revive does NOT imply that there was "death" after three minutes, but that appropriate measures were not taken to prevent recirculation failure. 8. The main point is that he is ignoring (and probably ignorant of) the substantial experimental evidence of survival of many or most features of anatomy and physiology of the brain after varying periods of post mortem ischemia, warm and cold; and in particular that synaptosomes appear rather hardy with respect to post mortem changes and with respect to freeze/thaw treatment. 9. Finally, he fails to distinguish between favorable and unfavorable conditions of cryonic suspension. Some of our Cryonics Institute patients have had to wait only a couple of minutes between clinical death and treatment, and by no stretch of the imagination could any reasonable person deny that they were then still mostly alive. Robert Ettinger Cryonics Institute Immortalist Society Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=5760