X-Message-Number: 5863 From: (Thomas Donaldson) Subject: Re: outmoded, backward notions of "death" Date: Fri, 1 Mar 1996 23:40:09 -0800 (PST) Greetings once more! How interesting it is to see one's name mentioned so often! In any case, I haven't been on the Net myself for some time because I've been busy with other things. HOWEVER: To Mr. Marshall Rice, I would point out first that even the notion of death of cells is a faulty one, short of total destruction. THIS INCLUDES BRAIN CELLS. Right now and for many years now neuroscientists have been actively working to find ways to push back the so-called "3 minute limit". As I understand the situation, with the proper drugs and treatment by experts, it is now possible to bring someone back after TEN MINUTES AT ROOM TEMPERATURE. (Note that this is an increase of 7 minutes). This entire line of investigation really started when Hossmann and Sato, in 1969, found that they could revive the brains of cats after ONE HOUR at room temperature (cf SCIENCE, where they published their paper. I can't get the cite for you now without going offline, and if you want to actually search out original papers rather than just repeat what you have heard, then all the better. And if you really do start exploring this matter for yourself, you will find first that your beliefs are badly out of date, and second that I have done no more than repeat the beliefs of scientific workers in the area. Hossmann and Kato, with their 1969 experiment, raised strong questions about the entire issue of brain death and its reversibility. Neuroscientists still feel the reverberations). So what does this tell us about the "3 minute limit"? Well, I guess there wasn't any such limit. Do we assume now that we have a "10 minute limit" instead? What do we do when it lengthens to 12 minutes? Start talking about a "12 minute limit"? Do you seriously believe that a present inability to bring someone back to life after X minutes means that we will never be able to bring them back after X + 1 minutes? X + 2 minutes? At some point it becomes wise to take a more general view. You have heard the comments about information by other cryonicists here. I would not claim that is a complete solution, since we need to know WHAT information, but it is miles ahead of simply accepting current abilities as the best we will ever have. One further error you make in discussing whether or not it will be possible to recover a high percentage of our brain connections comes from an obvious implicit belief that such recovery must happen sequentially: ie. one day someone gets to work and says, ah, this connects to that, and this connects to that, ... and so on for thousands of years. NOT AT ALL. If and when recovery becomes possible, it will clearly happen by looking at our brain in parallel, with many cooperating systems simultaneously working. That, of course, is essentially the way our bodies and even our brains work now: biochemistry works on lots of molecules at once, not at one at a time. Even in the very early days of cryonics (the late 60's) cryonicists were thinking about how repair might be done. One early suggestion was that of a highly modified virus. No, this doesn't mean just ONE virus, it meant many of them, all working at the same time. Now such ideas have come to be called nano- technology, and nanotechnology of various kinds has started to raise its head in many other contexts, too. And don't think that we stopped with viruses... that original idea was only a start. Nor should it be seen as unprecedented: a drug basically consists of a special molecule which when put into the proper milieu begins to work on many other molecules in your body, in parallel because there are many molecules of drug. So the next step from that would be a set of cooperating drugs ... and from that we can see how any repair system could be arbitrarily complex. So let us suppose that we DO find ways to repair our injured brains (and forget for a moment that cryonic suspension may soon improve to such an extent that our brains are no longer injured). Will we be in that repaired brain? Suppose all the connections had been broken, but that by careful examination of the clues left by the damage, every connection had been recovered. Are you going to claim that we are then gone? Just what physical damage will cause us to disappear? We have just as many grounds to believe that we would awaken (in this case) as we have to believe that we will be the same person tomorrow as we are today. We are not sets of molecules, or even cells, but a structure formed of these molecules and cells, which change constantly: much more like a wave or a waterfall than like a rock. That is what cryonicists mean when they speak of the INFORMATION. Yes, you may argue against this criterion if you wish, but please don't fall back on inadequate notions of "death". If you want more information, send a direct message to me and I can get you started. If you really want to argue against cryonics, and you aren't just playing, then you will not do so without knowing more about why we think it stands a significant chance of success. Best and even long long life, Thomas Donaldson Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=5863