X-Message-Number: 6437 Date: 04 Jul 96 00:09:24 EDT From: Paul Wakfer <> Subject: SCI.CRYONICS The Prometheus Project Subject: SCI.CRYONICS Announcing: The Prometheus Project The most significant fact to be reported here is that with 10 days of solicitation via email within a group of 22 middle to upper-income cryonicists, I have been able to elicit pledges of $102,000.00 per year, or $1,020,000.00 payable over the 10 year life of the project which I proposed to them. These pledges have been made by 1 foundation (not cryonics related) and 13 individuals, one of them outside the original group. The project which I proposed and which was greeted so enthusiastically and supported so strongly was that same project that Brian Wowk has been talking about on this forum for the past several days: The convincing demonstration of fully reversible mammalian brain cryopreservation within 10 years and the peer reviewed journal publication thereof. Because of its audacity and life- providing purpose we have named it: The Prometheus Project. It will be conducted by a for-profit corporation to be formed for this immediate purpose and for the longer-range purpose of producing fully reversible whole-body suspended animation. At this time only solid pledges of $1000.00 or more per year for 10 years are requested. When a total of over $1,000,000.00 per year has been pledged, a company will be formed, share purchase contracts will be signed by all pledgers, the first year's payments will be collected and shares issued, and the project will begin. In accordance with SEC regulations, I must state that this announcement is not a solicitation for the purpose of purchasing shares in any corporation. Needless to say, it is my strong belief, and one I sincerely hope that you will share with me after reading this report, that the most rewarding aspect of the successful completion of The Prometheus Project will be the almost certain opportunity for each of us to live vastly extended, healthy lives. So read on dear friends and become as excited and as optimistic as I and my follow pledgers are, at this entirely realistic chance to rid ourselves of that which hangs over our heads from the day we come into existence, which steals from us a lifetime of accumulated knowledge and wisdom, and finally, which removes any chance for happiness by sending us all into oblivion, that ultimate tyrant Death. A Plea for Guidance and Help Before, you read further I wish to make it abundantly clear, that while the general purpose of The Prometheus Project is settled, the details of its accomplishment and funding (and even its name, for that matter) are not cast in stone. I very much need the help of all of you, your suggestions, your ideas, and, of course, your pledges, in order to accomplish this "promethean" goal which I and my associates have set for ourselves. Please, critique our ideas by all means. Please, give us your brilliant new and better ideas to replace them with, or even your not so brilliant but very wise and practical ones. This project is an honest and very sincere non-partisan attempt to accomplish what we all want, to find a realistic way to get the research done which will virtually ensure that all of us will have the chance to see, to enjoy, and to take part in the endless and unimaginable adventures which await us in the world's future. The Purpose of The Prometheus Project The purpose of The Prometheus Project is to demonstrate by methods which will be convincing to the public and will be published in a peer reviewed scientific journal, the restoration to normal physiological and mental functioning of a mammalian brain which has been preserved and stored at a temperature below -140xC for at least 6 months. Logical Necessity of The Prometheus Project for Those Who Wish to Stay Alive The Problem: 1. Unless major scientific anti-aging advances are made, every one of us faces the virtually certain inability of our body to sustain its life within a period of 125 years minus our present age. If you are over 75 years old, the chance of major anti-aging and rejuvenating scientific advances being made soon enough to allow you to live a vastly extended healthy lifetime is virtually zero. If you are over 50 years old, the chance of this is still extremely small. Even if you are only 25 years old, the chance is marginal at best. 2. In order to continue to live, each of us needs a "time machine" to transport him or her, at least mentally intact, into the future. At present there is no method with the proven ability to do this. Burial, and cremation ensure complete destruction of the body, brain and mind. Even the best current methods of chemical or cryogenic preservation result in massive damage to the body and brain from which any future recovery is at best very uncertain. 3. Furthermore, it has not been proven, and may not even be true that the brain structures which determine our memories, our personality and all of our other precious individual mental attributes are being well preserved through current agonal and cryopreservation processes. 4. The idea of cryonics has been around for 30 years now and the number of people actually signed up has only grown to between 600 and 700. 5. Because of the length of time that it has been around, the publicity which such a radical idea has received, and the plot/entertainment value of such a sensational theme, the cryonics idea is now very widely known. 6. Yet cryonics as currently practiced, remains small and possibly unstable over the long term. Therefore, even if our mental attributes are being preserved through the current agonal and cryopreservation processes, and *can* be fully restored, most people have little confidence that anyone cryopreserved today will reach, still preserved, that possibly far future time when advanced technology *will* be able to effect the necessary restoration. 7. In spite of the multitude of deathist memes in our society (I'll have had enough; over-crowding of the planet; make a place for the young ones; I'll live on in my children; necessary to insure creativity; it's natural; want to be reincarnated; want to go to heaven; etc. etc. etc.), there are still 100's of thousands if not 10's of millions of people in North America who truly love life and would very much like to have a lot more of it so long as they could remain mentally and physically healthy. 8. The vast majority of even those who have not accepted the deathist memes will never sign-up for nor support cryonics while they remain relatively healthy, because, being small and unproven it has so little chance of saving them. Instead, they prefer to put any "extra" money into anti- aging methods and research aimed at extending their first "life cycle", giving little thought to the possibility of a *second* "life cycle". The Solution: 1. There does exist a method which has been shown to allow the preservation of a complex organ with no freezing injury at all. With this method, viable rabbit kidney's have been recovered from temperatures as low as -40xC, with recovery from much colder temperatures expected soon. This method is called vitrification. It involves turning the organ to be preserved into a glassy substance, cooling it to cryogenic temperatures, and keeping it stored at those temperatures until such time as we wish to recover it for use. Just as glass is fluid at high temperatures and becomes solid as it is cooled to lower temperatures without any crystallization occurring, so too biological tissue by having its internal water largely replaced with a special solution, can be made to behave like glass and incur no disruptive crystalline formation when it is cooled, even to the temperature of -140xC. (This temperature will be used because it is almost universally agreed by the cryobiological science community that it is sufficiently low to allow storage for several hundred years if necessary with negligible deterioration.) The trick is, however, to use a solution and a method of water removal which does not in itself irreversibly damage the biological tissue. 2. Because this vitrification protocol is organ specific, the protocol for kidneys will not work for many other organs. Therefore, if we are ever to achieve suspended animation of the whole human body, we must proceed to make it work for other organs. The most important human organ and therefore the logical starting point, of course, is the brain. 3. The scientist who has developed this method of preservation for rabbit kidneys has stated that he does not see any technical reason why this method, with suitable modifications should not be applicable to any mammalian organ including the brain. Furthermore, he has estimated that for any particular organ, the necessary modifications should be able to be discovered and perfected within a time-span of 10 years and with a project budget of under a million dollars per year. 4. Neuroscience developments and techniques for assessing brain function directly should allow us to convincingly demonstrate the mental attributes of an isolated or in-situ mammalian brain. 5. If we can produce a method by which first a mammalian and then a human brain can be placed in long-term biological stasis and recovered with its functionality including all mental attributes unquestionably alive and complete, we will have the proof that death can be defeated - that in principal, a life can be extended indefinitely. Once convincingly demonstrable, fully reversible, long-term preservation of the brain has been achieved, the mainstream medical and scientific community will accept the scientific validity of the cryonics idea. Major public and private money will be spent to develop methods of providing a body for a restored brain, and to perfect whole-body long-term suspended animation, if possible. The practice of preserving the brain, and later the whole- body, if possible, will become an optional standard medical procedure for the terminally ill and the laws will be changed to accommodate this new paradigm. The Logic of The Prometheus Project Funding Method 1. Those persons who have a great desire for vastly extended life *will* sincerely pledge major amounts to a demonstrably fully reversible brain cryopreservation project if they are convinced that it is necessary, that it has sound planning which will enable it to succeed if it is funded, and if their pledges are not due until it *does* have sound planning and *is* fully funded. 2. Most of those with incomes over $50K per year (and certainly all of those with incomes over $100K per year) should be able to afford to forgo the present spending of $5-10K per year (at least if tax deductible) without degrading their life-style in any way detrimental to their health and longevity. 3. Within the cryonics and life-extension community, there are well over 200 people who fit this category. Hence, there are a more than sufficient number of people to fund a project which will scientifically demonstrate that long-term reversible brain preservation will work, and therefore, that will be virtually certain to vastly increase the chance of their lives having the potential of immortality. 4. The Prometheus Project defined here is an attainable and fundable goal. It is realistic to expect to obtain between 100 and 200 pledges of amounts between $5,000.00 per year and $10,000.00 per year each for 10 years. And this has now been proven by the test case described herein. Organization of the Collection of the Pledges As founder of The Prometheus Project, I, Paul Wakfer, one of the $10,000.00 per year pledgers, will be the person who accepts the pledges and will be founder and the interim president of the corporation which is formed once the necessary total of one million dollars per year for 10 years is reached until The Prometheus Project officially begins. Pledges will be made for the purpose of purchasing shares in a yet to be formed for-profit corporation over a 10 year period at a fixed price of $100.00 per share with the requirement that an equal amount must be pledged for each of the 10 years. Pledges will not be due until the entire $1M per year has been pledged and the pledgers have approved the scientific plan of the project and the business plan of the corporation. Any pledger who does not approve of these plans may withdraw his pledge before The Prometheus Project begins. The signification of approval to proceed will be done by each pledger signing a legally binding Share Purchase Agreement. This is necessary to insure that the required funding will be forthcoming each year after the project begins. Pledgers who wish to have a tax deduction for the amount of their contribution are encouraged to make arrangements with one of the cryonics organizations or life extension societies which have the ability to issue tax deductible receipts for charitable donations. After The Prometheus Project has begun, those organizations will then use the donated moneys to purchase shares under the same terms as other individual or corporate purchasers. Cryonics organizations which have this capability (or will soon) are: Alcor Life Extension Foundation American Cryonics Society CryoCare Foundation The Immortalist Society Earlier today all cryonics organizations were contacted and sent an advance copy of this announcement. I have asked each of them for their help in promoting the success of The Prometheus Project and have invited and encouraged each of them to invest in, and to support this project which will be so beneficial for themselves, their members and their cryonics patients. In addition, The Life Extension Foundation has agreed to accept donations, to issue tax deductible receipts, and to make share purchases under the contractual terms necessary for funding The Prometheus Project. The Prometheus Project will be delighted to accept any pledge of more than $1000.00 per year, but for administrative and share purchase purposes requires that all pledges be made in units of $100.00 per year. Again it should be noted that all pledges must be for the same amount per year for all 10 years. Pledges will be organized into the following categories, with certificates and possibly some other form of acknowledgement issued for each category. $50,000 a year Platinum 10,000 a year Gold 5,000 a year Silver 1,000 a year Bronze Of the 14 pledges received so far: 8 are for $10,000.00 per year for 10 years 4 are for $5,000.00 per year for 10 years 2 are for $1,000.00 per year for 10 years The total is $102,000.00 per year for 10 years! That is over 10% of the total funding needed for the entire project from only 14 cryonicists, and these people are not even the high rollers of the cryonics movement. Are you going to sit there and let them prove to everyone by their actions, that they value their lives more than *you* value yours? While pledges are being received and are building to the total of $1M per year required, the scientific plan of The Prometheus Project and the business plan of the corporation which will execute it, will be developed and prepared. Any help that can be contributed to this part of the project (or any other part) is very much welcomed. I plan to publish these on this forum even in unfinished form as they are developed and prepared. I'm going to end this installment here and continue with second and possibly third postings of the initial ideas. This project is very much a boot-strap process. For many reasons, I believe that is the *best* way to accomplish it. I look forward to your questions and suggestions and you can be sure that if the ideas are worthy, they *will* be incorporated into the developing project plans. Before I end, however, I wish to leave you with some thoughts. For several weeks now, I have been putting a lot of thought toward what I am now calling "The Prometheus Project" and I very strongly believe that each of us who really wants to live should begin pushing this project constantly and continuously with all the time, money and life-force which he or she can afford without degrading his or her current life below a certainly minimum acceptable quality (which granted will be different for each individual). I have become convinced that if any of us are to survive long- term, one way or the other, this project *must* be accomplished. I believe that The Prometheus Project must be non-partisan and strongly supported by all organizations because it is much too big for any one cryonics organization. We need all the ideas and help we can get from any source whatever and *I* pledge to design and discuss it with absolutely no negativity, innuendo or bias with regard to any particular organizations or individuals. I expect each organization and each cryonicist to understand why it will be beneficial for them to strongly support the project. We must perform the discussion of this project on the internet and in all our communications and continue it non-stop, and relentlessly until we have achieved the funding goal. I ask every one of you to include it with every thing you write, hammering away at the idea incessantly, never letting up for a moment until we have done it. The Prometheus Project is not a *charity* for which I am begging you to give up part of your life for some purpose exterior to you which *I* happen to think is important. No! What I am asking is nothing more nor less than that you honor *yourself*, that exquisite individual consciousness which is yours alone. -- Paul -- !!!!! REVERSIBLE BRAIN CRYOPRESERVATION *CAN* BE ACHIEVED IN 10 YEARS !!!!! Paul Wakfer email: Voice/Fax: Pager: US: 1220 E Washington St #24, Colton, CA 92324 909-481-4433 800-805-2870 Canada: 238 Davenport Rd #240, Toronto, ON M5R 1J6 416-968-6291 416-446-9461 (currently in Canada) Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=6437