X-Message-Number: 6598 Date: Wed, 24 Jul 1996 14:36:57 +0200 (MET DST) From: Eugene Leitl <> Subject: ARTERIAL pCO2 IN LAB ANIMALS (fwd) ---------- Forwarded message ---------- Date: 22 Jul 1996 19:32:58 GMT From: JAN CZEKAJEWSKI <> To: "bionet.neuroscience mail newsgroup" <> Subject: ARTERIAL pCO2 IN LAB ANIMALS Arterial pCO2 is one of the variables which interferes other physiological parameters in anesthetized animals during surgical experiments. It needs to be kept at more or less constant level during experiment. It has been established that the value of arterial pCO2 is identical to the end-tidal CO2. End-tidal CO2 measurement in larger animals and in humans are not a problem because of the presence of sufficient volume of available respiratory gases while the measurements in very small animals such as in rats and mice were difficult because of low volume of gas. In rats and mice, arterial pCO2 can be measured without drawing blood from artery. We developed Micro-capnometer (end-tidal CO2 meter) that utilizes low air sample flow rates (5, 20 ml/min) and is ideal for laboratory animals especially, for rats and mice. The device has also the capability of determining the respiration rate by counting the period from the wave pattern of CO2 concentration. If you are interested in this device and its application in rats and mice, please e-mail your street address. I will send you all the necessary information. JAN Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=6598