X-Message-Number: 7209
Date: Sat, 23 Nov 1996 17:45:52 -0800
From: Tim Freeman <>
Subject: Quality Control in Cryonics

I haven't been reading the list for a while due to an email snafu, so
I skimmed the archives.  I found cryomsg 7154 by Steve Harris on 17
Nov 96 suggesting a few quality control measures that could be taken
during suspensions:

* CPK-BB levels (this is a hormone secreted when tissue is damaged, so
  lower is better, right?)
* A-V O2 differences (functioning tissue uses up O2, so more is
  better, right?)
* lactates (tissue trying to function in the absence of O2 produces
  these, so less is better, right?)
* temperature descent curves (faster is better, according to Steve's
  post.) 

(Chances are that one or more of the assertions by me in the
parentheses above are wrong, BTW.  On the net, the best way to get
accurate information is to post inaccurate information.  Sorry.)

All of these would be done during the initial cooldown to slightly
above 0 degress C, right?  Otherwise I would not expect enough
metabolism going on or enough blood to be present for the measures to
be meaningful.

I expected to see followup posts stating one of the following:

* We already publish these.  See our newletter published on ...
* These are the wrong things to measure because ...
* We will measure and publish these with our next suspension.
* We can't measure these because they cost $...

but I didn't see any of them in the messages mentioning "Quality
Control" in their subjects, or the other messages I skimmed.  Is the
proposal worth doing or not?  What is the plan?

(Actually, I also expected to see Steve Harris to go first and say
where BioPreservation published the measures for their suspensions to
date.)

Tim Freeman


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