X-Message-Number: 762 Date: 23 Apr 92 06:04:58 EDT From: "Steven B. Harris" <> Subject: Alcor Nevada Minutes Errors Greetings to Alcor Nevada, Nevada's a great name for a cryonics state, eh? Maybe the storage facility is destined to be there after all. And I'm glad you folks are going great guns on the training. I do have some negative comments on your minutes, however. Regarding the story of French Doctors pretreating people with Hydergine against the possibility of brain ischemia, Jack Z. Yetiv, M.D., Ph.D. wrote a book several years ago called _Popular Nutrition Practices_, in which he devotes a chapter to _Pearson and Shaw's Life Extension_. One of the things he attempted to do there was substantiate some of Pearson and Shaw's claims about Hydergine, but he was unable to. According to Sandoz, the makers and marketers of Hydergine, Hydergine has NEVER been used in human resuscitation, and is NOT used as a pre-op. Actually, Hydergine is hardly the magic drug that Pearson and Shaw claim, and Sandoz is not that excited about it. For instance, Pearson and Shaw claim that Sandoz spends 40% of its research budget on Hydergine, and that it is the fifth most popular drug in the world, and number one in France. Sandoz, however, says the research figure is more like 3% (and that mainly to look at different delivery systems) and that the other figures about popularity are ridiculous (which with a little thought one might have realized). And so on. From my own experience, let me reinforce this: do not trust Pearson and Shaw about food supplement advice. These are well- meaning people with an appealing philosophical stance, but they are neither physicians nor scientists (definition: a scientist is one who does scientific studies and publishes them in peer- reviewed scientific journals). Instead, Pearson and Shaw are the kind of people who lack detailed knowledge in an area where it is critical. I've seen them confuse inosine with inositol in the explanation of how Valium works (another story). Nor are they able to interpret experimental results: they will tell their readers that Hydergine slows lipofuscin accumulation in "mam- malian neurons," but fail to add that this result is for rodent neuroblastoma in vitro [Say what? -- you take those pills because they worked on cancerous rat neurons in a dish?] Actually, in vivo experiments in intact animals have failed to show an anti-lipofuscin accumulation effect for Hydergine. In any case, with Pearson and Shaw I'm reminded of Twain's aphorism about health books: watch that you don't die of a misprint. Or as the famous gerontologist Ed Schneider says about the pair: "They're fun. I just wish they weren't in aging." --- In the matter of the Pilgeram case, I am a bit shocked that Eric would post something to the net indirectly critical of Alcor, without doing his homework. It's fine to criticize Alcor, but get the facts right first! I'll relay directly what Mike Darwin has to say on this: "I am rarely moved to comment on issue political these days. However, some errors of fact are so egregious and so without basis on reality that they cannot be left uncorrected. I am referring here to comments by Eric Klien to the effect that Mrs. Laurence Pilgeram, the Alcor patient whose continued suspension is in jeopardy, was frozen against her wishes, and that "no one testified differently." This is untrue. Mrs. Pilgeram ex- pressed her desire for cryonic suspension personally to both Carlos Mondragon (Alcor CEO) and me. I have testified to this effect under oath on several occasions. While it is fair to say that Mrs. Pilgeram was not a wild enthusiast about cryonics, she seemed at ease with her decision in favor of cryonic suspension. I would caution Mr. Klien and others to be very careful of their facts where human lives hang in the balance. A simple phone call to Alcor or to me would have resolved the factual matter in this issue." -- Mike Darwin I have to agree with Mike on this one. Talk to a few people closer to the facts before making factual assertions, folks! If you've heard second-hand rumors, post them as such and ask for the truth. See also Cryonics Magazine Oct., 1990, p 22. for more on this particular conflict (I trust I'm not giving away anything here, since Eric has already posted quite enough detail for anyone with a triple digit IQ to figure out which case out of Alcor's relatively few is being described there). -- Steve Harris Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=762