X-Message-Number: 7692
Date: Mon, 17 Feb 1997 08:38:41 MST
From: "Richard Schroeppel" <>
Subject: DMF toxicity

>   Re South Africa, please bear in mind that their Medicines Control Council
    prohibited the further application of "Virodene" because it contains "a
    highly toxic industrial solvent, dimethylformamide (DMF), which can cause
    fatal liver damage and has been linked to the development of cancer."

Most medicines are toxic in sufficient dosage.  AZT certainly is.
Without more information on dosage, protocols, etc. the toxicity of DMF
alone seems insufficient reason to prohibit trials.

Rich Schroeppel   

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