X-Message-Number: 8075
Date: Mon, 14 Apr 1997 16:36:58 -0700 (PDT)
From: Olaf Henny <>
Subject: CRYONICS Re: CryoNet #8060 - #8068

>>I wrote the following in an earlier message and I am sorry to say, 
that I did not receive a reply from Prof. Peter Sharp or anybody else 
from the Roslin Institute:
>"""""""""""""""""""""""""""""""""""""""""""""""""""""
>In Message #7930 Robert Ettinger wrote:
>
>>3. Olaf Henny (#7913) makes me wonder if I bungled in skimming the news on
>>Dolly. Olaf says the offspring was from an egg (sheep B), tickled by an adult
>>udder cell nucleus from sheep A, then gestated in sheep C, and that the DNA
>>in the udder cell was not expressed or passed on. Am I confused? If the above
>>is correct, it would not be cloning at all--just another slight variation of
>>parthenogenesis. My understanding was that the udder cell nucleus was the
>>sole provider of the genetic material of the offspring--that's what made it
>>cloning, use of an adult somatic cell to reproduce its own genotype.
>
>In  Message 7913 I summarized my understanding of the procedure used 
in cloning as follows:
>-----------------------------------------------------------
>The no doubt significant accomplishment of Ian Wilmut and 
>Keith Campbell was, that they managed to 'bully' through 
>starvation an egg of sheep A into accepting the cell of an 
>udder of sheep B in lieu of a sperm.  The resulting zygote 
>was then implanted into the uterus of sheep C and brought to 
>term in the usual manner of natural propagation.  The 
>accomplishment of these Scottish scientists lay in the 
>acceptance of the udder cell in lieu of sperm and complete 
>dominance of the DNA of the egg, which was presumably due to 
>the inability of a somatic cell to assert its own DNA.
>------------------------------------------------------------
>This was based on press reports I have read, which are not 
>necessarily reliable. I have therefore after Robert Ettinger's 
>questioning endeavored to search the net for more pertinent 
>information and quickly got mired in a proliferation of 
>sensationalized press reports.  I have therefore sent an e-mail 
>to Dr. Ian Wilmut requesting an abstract or brief summary of the 
>steps taken in the successful cloning through the following website:
>
>Roslin Institute
>             Current projects: January 1997
>
>Programme 03: 
>Developmental and reproductive biology of farm animals 
>Programme Coordinator: Prof. Peter Sharp
>
><http://www.ri.bbsrc.ac.uk/library/projects/prog03.html>
>
>If and when I receive a reply, I will definitely post it here.
>
>Olaf Henny
"""""""""""""""""""""""""""""""""""""""""""""""""""""""""""""
Olaf Henny

Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=8075