X-Message-Number: 860 Date: 28 May 92 05:52:43 EDT From: "Steven B. Harris" <> Subject: High Temp Patient Storage Dear Fellow Cryonicists: Thanks for the Alcor New York News in electronic form. I was interested in the discussions of higher temperature patient storage, and in response to the invitation for thoughts on this matter I hereby offer some ideas that I came up with some time ago, and have been kicking around with a few cryonicists ever since. First, let me point out that for thermal stability reasons, storage at any temperature is made much easier by addition of a thermal ballast. A thermal ballast is something that undergoes a phase change at the temperature you want, so that addition or subtraction of heat doesn't change the temperature much (it only changes the phase). Examples of such ballasts are the ice in your drink which keeps it at a constant 0 C. until all the ice is gone, and the liquid nitrogen currently used for cryonics storage, which boils when heat is added but doesn't change temperature. It's a bit difficult to identify ballast materials in the range we want, but in 1987 I did test some candidate materials at the Alcor lab (then in Fullerton) and discovered that out of a number of candidate compounds, ethyl chloride (chloroethane, C2H5Cl) in particular forms nice crystals at its melting point of -135 C and seems to be generally well behaved, with an adequate temperature "knee" as the phase changes. Moreover, ethyl chloride in industrial purity is cheap, as Michael Paulle's recent research has demonstrated (thanks, Michael!). It's the best candidate compound I've identified so far. The system I envision works like this: patients are suspended in sleeping bags in standard dewars, hanging in dry nitrogen at -135 C. (Dewars will need to be sealed to keep out moisture). The cooling unit which hangs along-side the patient is a fan and a long hermetically sealed cylinder of ethyl chloride, at the heart of which lies a multiply coiled heat exchanger tube, into which is introduced liquid nitrogen. In this system, when the outside of the cooling cylinder begins to warm, indicating that most or all of the ethyl chloride "ice" has melted, a thermostat triggers a valve which admits liquid nitrogen under pressure from a standard LS-160 liquid nitrogen tank at a fixed flow rate, slowly freezing the ethyl chloride until a sudden temperature drop at the reservoir surface indicates that all the liquid is again frozen. At this point the nitrogen flow is stopped until the cycle begins again. It may be possible to supplement the system with fiberoptic ice sensors. Power outage protection need consist of only enough battery backup to run the sensor, valve, and computer (not much), since cooling (as today) will be done by liquid nitrogen. Such a system will not be completely free of temperature swings, of course, but at its single design temperature it may be nearly as good as much more expensive helium cryo-refrigeration systems. To make the system _really_ thermally stable at the patient level, the "electric blanket" idea already discussed as part of an alternative cooling system, might be used. I believe that such a thermal blanket would be totally impractical in the suggested use of shielding a patient at -125 (say) from liquid nitrogen at -196 C (unless the patient was in a second nested dewar), but it might well be very useful for shielding a patient at -125 from swings in air temp from -140 to -130 C which could occur as an ethyl chloride ballast was being recharged. A workable system, then, might well be a hybrid of those proposed in the Alcor NY news, with the exception that our familiar liquid nitrogen could be used in the ballasted coldfinger, instead of helium. -- Steve Harris Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=860