X-Message-Number: 8702 Date: Fri, 31 Oct 1997 15:10:29 -0800 (PST) From: Doug Skrecky <> Subject: 18'th update on fly longevity experiments This is the eighteenth update of my fly experiments. The onion 4X bottle is turning out unexpectedly to be a big winner, with a day 45 survival of 50%. By comparison by day 26, survivals in 5 out of 6 control bottles were lower than this. Although high dose onion powder looks very promising, I will need to replicate these good results before believing them. Cinnamon with a day 45 survival of 35% also looks promising. I will be testing chitosan in the next run in combination with various fat containing supplements, including onion and cinnamon. We'll see then if chitosan's fat absorbing ability improves survivals yet further. Adding yeast to the control bottles looks to be reducing survival. Under sterile laboratory conditions adding yeast can increase survival slightly. Since my own somewhat unsanitary experiments find yeast to be deleterious, I take this to be an indication that pathogens are a longevity limiting factor with my experiments. Nontoxic doses of onion, sage and cinnamon may be offering life span extension primarily by inhibiting pathogen growth. This renders my results questionable to say the least and before any supplement can be conclusively stated to be beneficial to fly longevity, experiments conducted under truly sterile conditions would be needed. I will attempt to improve my own quality control procedures in the next run. Those with sharp eyes may notice that one of the paprika doped flies sprang back to life on day 41, after being declared a goner on day 36. Sixth Run SURVIVAL ON DAY BB# Supplement #10 #14 #18 #26 #36 #41 #45 1 cntl 1 93% 87% 80% 47% 20% 20% 7% 1 cntl 1 +yeast 90 85 70 45 20 5 5 1 B complex 94 82 71 47 12 12 6 1 B complex 4X 83 78 67 44 6 0 - 1 chitosan 86 79 64 36 7 0 - 1 chitosan 4X 83 83 83 75 42 33 25 1 chondroitin sulfate 89 83 83 78 56 33 11 1 chondroitin sulfate 4X 88 82 65 65 24 12 6 1 chromium picolinate 75 65 60 50 25 10 5 1 chromium picolinate 4X 92 88 83 79 58 33 21 1 cinnamon 90 85 85 75 55 50 35 1 cinnamon 4X 93 87 80 40 33 20 13 1 DMAE bitartrate 85 62 62 46 31 15 15 1 DMAE bitartrate 4X 78 78 78 56 44 22 6 2 cntl 2 89 82 67 37 15 7 4 2 cntl 2 +yeast 82 82 64 18 5 5 5 2 french mushroom 80 72 56 40 8 0 - 2 french mushroom 4X 74 43 43 26 4 4 4 2 kava kava 79 67 54 38 25 0 - 2 kava kava 4X 83 75 64 56 22 11 6 2 onion 77 73 68 32 18 9 9 2 onion 4X 81 75 75 63 56 56 50 2 paprika, spanish 84 76 60 48 20 24 12 2 paprika, spanish 4X 94 82 76 59 24 12 12 2 l-proline 73 60 53 33 20 20 13 2 l-proline 4X 94 81 75 59 34 19 9 2 sage 95 68 63 32 16 16 5 2 sage 4X 95 90 90 85 60 35 30 2 sodium citrate 62 46 46 38 15 8 8 2 sodium citrate 4X 89 83 61 33 28 11 11 3 cntl 3 77 68 64 59 18 14 5 3 cntl 3 +yeast 92 85 62 15 0 - - 3 St John's Wort 85 75 70 40 15 10 0 3 St John's Wort 4X 72 50 39 0 - - - 3 sumac 43 43 43 36 14 7 7 3 sumac 4X 79 71 57 36 29 21 21 3 wild yam 50 42 25 25 8 8 0 3 wild yam 4X 82 55 50 32 14 5 5 Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=8702