X-Message-Number: 8980 Date: Thu, 8 Jan 1998 20:48:44 -0800 (PST) From: Doug Skrecky <> Subject: 19'th update on fly longevity experiments This is the nineteenth update of my fly experiments. There was a delay in starting the 7'th run, since my breeding stock unexpectedly almost died out. I restarted some more breeding bottles and the flies seem to be doing well now. Onion 4X did a good job of "squaring the survival curve" in run #6. No onion 4X flies outlived the longest lived control flies, so no antiaging effect could be detected. I suspect that high doses of onion powder may be acting as a non-toxic bactericide, something I have been searching for a long time. This stimulated me to test combinations of onion 4X and some other supplements in the 7'th run. The trouble with my experiments up till now, is that early mortality is so high, that no antiaging supplement can be expected to significantly increase life span, unless it also acts against early mortality as well. Since I am assuming that early deaths are due partly to pathogens, then antiaging supplements, which do not also act as a bactericides, may not increase life span significantly. It is this dual action (bactericidal & antiaging) that may account for the good results with paprika, sage and sumac in the 6'th run. For the sixth run I used cool water that had been boiled. In the seventh run, except for a few control bottles, I am adding water that is still boiling, so as to help sterilize the fly food/supplement powder mixtures. We'll see if this makes a difference. Sixth Run SURVIVAL ON DAY BB# Supplement #10 #14 #18 #26 #36 #41 #45 #52 #57 #62 #65 1 cntl 1 93% 87% 80% 47% 20% 20% 7% 7% 0% - - 1 cntl 1 +yeast 90 85 70 45 20 5 5 5 0 - - 1 B complex 94 82 71 47 12 12 6 0 - - - 1 B complex 4X 83 78 67 44 6 0 - - - - - 1 chitosan 86 79 64 36 7 0 - - - - - 1 chitosan 4X 83 83 83 75 42 33 25 8 8 0 - 1 chondroitin sulfate 89 83 83 78 56 33 11 0 - - - 1 chondroitin sulfate 4X 88 82 65 65 24 12 6 0 - - - 1 chromium picolinate 75 65 60 50 25 10 5 5 5 0 - 1 chromium picolinate 4X 92 88 83 79 58 33 21 13 4 0 - 1 cinnamon 90 85 85 75 55 50 35 10 0 - - 1 cinnamon 4X 93 87 80 40 33 20 13 7 0 - - 1 DMAE bitartrate 85 62 62 46 31 15 15 0 - - - 1 DMAE bitartrate 4X 78 78 78 56 44 22 6 0 - - - 2 cntl 2 89 82 67 37 15 7 4 0 - - - 2 cntl 2 +yeast 82 82 64 18 5 5 5 5 0 - - 2 french mushroom 80 72 56 40 8 0 - - - - - 2 french mushroom 4X 74 43 43 26 4 4 4 0 - - - 2 kava kava 79 67 54 38 25 0 - - - - - 2 kava kava 4X 83 75 64 56 22 11 6 3 0 - - 2 onion 77 73 68 32 18 9 9 0 - - - 2 onion 4X 81 75 75 63 56 56 50 25 0 - - 2 paprika, spanish 84 76 60 48 20 24 12 4 4 4 4 2 paprika, spanish 4X 94 82 76 59 24 12 12 6 0 - - 2 l-proline 73 60 53 33 20 20 13 7 0 - - 2 l-proline 4X 94 81 75 59 34 19 9 6 3 0 - 2 sage 95 68 63 32 16 16 5 0 - - - 2 sage 4X 95 90 90 85 60 35 30 20 15 10 0 2 sodium citrate 62 46 46 38 15 8 8 8 0 - - 2 sodium citrate 4X 89 83 61 33 28 11 11 6 6 0 - 3 cntl 3 77 68 64 59 18 14 5 5 0 - - 3 cntl 3 +yeast 92 85 62 15 0 - - - - - - 3 St John's Wort 85 75 70 40 15 10 0 - - - - 3 St John's Wort 4X 72 50 39 0 - - - - - - - 3 sumac 43 43 43 36 14 7 7 0 - - - 3 sumac 4X 79 71 57 36 29 21 21 21 7 7 0 3 wild yam 50 42 25 25 8 8 0 - - - - 3 wild yam 4X 82 55 50 32 14 5 5 0 - - - Seventh Run BB# Supplement 1 cntl 1 1 hot cntl 1 (boiling water used - same as with supplement bottles) 1 creatine: 1/16'th T (teaspoon) 1 creatine 4X: 1/4 T 1 fennel: 1/16 T 1 fennel 4X: 1/4 T 1 gaba: 1/16 T 1 gaba 4X: 1/4 T 1 garam masala: 1/16 T 1 garam masala 4X: 1/4 T 1 guggulipid: 1/4 capsule, 62.5 mg (1.56 mg guggulsterone) 1 guggulipid 4X: 1 capsule, 250 mg (6.25 mg guggulsterone) 1 hawthorn: 1/4 capsule, 125 mg 1 hawthorn 4X: 1 capsule, 500 mg 1 lemon peel: 1/16 T 1 lemon peel 4X: 1/4 T 1 l-lysine: 1/4 capsule, 125 mg 1 l-lysine 4X: 1 capsule 500 mg 1 l-ornithine: 1/4 capsule, 125 mg 1 l-ornithine 4X: 1 capsule, 500 mg 2 cntl 2 2 hot cntl 2 2 onion 4X: 1/4 T 2 onion 4X/chitosan 4X: 1 capsule, 300 mg 2 onion 4X/chitosan 8X: 2 capsules, 600 mg 2 onion 4X/chromium picolinate 4X: 1 capsule, 500 mcg 2 onion 4X/chromium picolinate 8X: 2 capsules, 1000 mcg 2 onion 4X/cinnamon: 1/16 T 2 onion 4X/cinnamon/chitosan 4X 2 onion 4X/paprika: 1/16 T 2 onion 4X/paprika/chitosan 4X 2 onion 4X/sage 4X: 1/4 T 2 onion 4X/sage 4X/chitosan 4X 3 cntl 3 3 hot cntl 3 3 shark cartilage: 1/4 capsule, 187.5 mg 3 shark cartilage 4X: 1 capsule, 750 mg 3 silymarin: 1 capsule, 50 mg 3 silymarin 4X: 4 capsules, 200 mg 3 thiodiproprionic acid: 1/16 T 3 thiodiproprionic acid 4X: 1/4 T 3 trimethylglycine: 125 mg (also called betaine) 3 trimethylglycine 4X: 500 mg 3 l-tyrosine: 1/4 capsule, 125 mg 3 l-tyrosine 4X: 1 capsule, 500 mg Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=8980