X-Message-Number: 9425 Date: Wed, 8 Apr 1998 14:03:53 -0400 (EDT) From: Charles Platt <> Subject: Damage to CI Patients On Wed, 8 Apr 1998, Bob Ettinger wrote: > The first project was precisely to repeat the CI sheep head work, as > faithfully as possible, and to evaluate the results in more detail than we > could do, using light and electron microscopy. All of this is irrelevant to the key points. 1. Pichugin gradually increased the concentration of glycerol in accordance with standard cryobiological practice. 2. The Cryonics Institute does not do this, when perfusing human patients. 3. Experienced cryobiologists will tell you that if you inflict 70% glycerol (by volume) in a single pass, this will inflict major damage. So, *why do you do it?* All you have said so far is that ramping up the concentration "caused problems." Do you mean it was inconvenient? Or what? The remainder of your message unfortunately takes a more personal line. > Recently Platt has been very downbeat, perhaps in part because CryoCare has > had years of slow growth, no growth, or negative growth. CryoCare has not had net negative growth. Our membership figures have been static, around 80, for the past 18 months, because we made a policy decision to avoid growth while concerning ourselves with other priorities. Our membership figures are published and you could have checked them before casting your aspersion. Before I wrote about The Cryonics Institute, I took the trouble to verify my facts. I wish you would show the same courtesy toward CryoCare. You have made many assertions that are factually wrong, and you would have known this if you had bothered to call me, or our Secretary Ben Best, or if you had simply checked our web page. I can't help wondering if it is more convenient for you NOT to check your facts, so that you are free to circulate misinformation in the hope that people will believe it. Incidentally, I note that The Cryonics Institute never publishes ANY data on its number of members or rate of growth. This is in accordance with a long-standing policy of secrecy, which I believe is unfortunate. Likewise, Cryonics Institute has never published real data about any of its human cases. > But as president of > CryoCare, it is hard to understand why he would say on Cryonet that he > believes a patient under IDEAL circumstances has only about a one in ten > thousand chance of rescue. This is not relevant to the discussion, but since you have attacked my integrity, I supposed I have to respond. There are many reasons for doubting my chances as a cryopatient: 1. Excellent chance of a federal law prohibiting cryonics, within the next fifty years. (Look at the hysteria over cloning.) Ironically this risk increases as cryonics becomes more plausible. 2. Good chance of backlash by extremist groups. They bomb abortion clinics; why not cryonics facilities? 3. If we succeed in convincing people that cryonics patients are not irrevocably dead, the FDA will broaden its mandate to control cryonics procedures. At that point, the procedures will become unaffordable, because every separate step in the protocol will have to be verified via cripplingly expensive animal studies. Moreover, the FDA may demand that existing patients, frozen with unapproved technology, must be exhumed. 4. Always a possibility that a cryonics organization will go bankrupt, fall into the hands of asset strippers, or suffer some other financial catastrophe that is too great to be covered by other organizations. This chance is significant because NO cryonics organization survives on membership dues alone; they all require donations. 5. Even under optimum circumstances, using the best modern techniques, I believe substantial damage to ultrastructure occurs, and I am unconvinced that nanotechnology will be capable of resolving it. The nanomachines may have the capability, but programming them to fix the damage would be like programming today's industrial robots to repair a crashed car. The problem is very different from building a new car. It is nontrivial. 6. People in the future may have priorities very different from ours. We certainly would spend some money to resuscitate people from the past, because we are curious about our past, and we value life. People of the future may feel differently. 7. Worse, people of the future may acquire cryonics patients for experimental procedures. From a future perspective, we may seem as unevolved as rats. Therefore, we may be treated like rats. Who can say? 8. Inflation coupled with a market crash may devalue patient funds to the point where they are insufficient to purchase liquid nitrogen. I could go on, but you get the gist. So, why bother with cryonics? Because, obviously, there are no better options, and a small chance is better than none. "Thinking positively" can be helpful, but it can also create a false sense of security. If we do not face problems in cryonics honestly, we lose the motivation to make improvements, and we end up performing some comforting rituals that don't have much scientific basis. I believe this may be what has happened at The Cryonics Institute. I continue working for a cryonics organization because I am fully aware of the very significant challenges facing us, and I wish to do what I can to mitigate them. I believe this is a rational response to a tough problem. I suggest this is more useful than fooling ourselves that "everything will work out" because no matter how much damage is caused today, those nice paternal figures of the future will sort it out for us. I believe this attitude has been the bane of cryonics, retarding progress for the past thirty years. > That would be a harsh and hasty judgment, certainly, but that is what he is > inviting. Bob, if you wish to attack my integrity, go ahead and do it honestly. Do not cloak it in this kind of nonsense, where you cast an aspersion and then shake your head solemnly and say, "Of course, if someone said that, it would be a hasty judgment." I know you are angry that I have stood up and itemized some very serious concerns about the damage that I believe CI is doing to patients. I know you are angry, also, because I wrote a long article a year ago, exposing Olga Visser's failed rat-heart experiments (which you supported rather recklessly with an amount in the region of $25,000). But surely this personal stuff is not relevant. The question is simply whether your vague claims regarding CI's perfusion and cooldown protocol are scientifically valid. I have spelled out, very specifically, some excellent reasons for believing that damage is caused. If I am wrong, I invite you to prove it. Here's a suggestion for a simple way to begin. I invite you to ask any experienced cryobiologist what he believes are the consequences of perfusing a patient with 75% glycerol (by volume), with no prior attempt to increase concentration gradually. Let's hear what an independent observer has to say about this. And let's leave my supposed pessimism, or CryoCare's supposed lack of membership growth, out of the picture. I doubt that anyone has much interest in reading your pejorative statements on these topics. --Charles Platt CryoCare Rate This Message: http://www.cryonet.org/cgi-bin/rate.cgi?msg=9425