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Msg  Description
# 0035 The Cryobiological Case For Cryonics
  General cryobiological background 2. Living adult animal brains 3. Living adult human and animal brain tissue 4. Living fetal human and animal brain tissue 5. Living human and animal isolated brain cells 6. Post-mortem human and animal brains 7. Post-mortem human spinal cord and . . . goal. Questions concerning maintenance of the brain after restoration are not cryobiological and can therefore . . . components of the brains of humans shortly after these humans have clinically died. Second, repair . . . Summary of general conclusions It can be stated quite firmly that cell bodies, cell membranes, . . . structure or brain function has been evaluated after freezing to low temperatures and thawing, robust . . . of death, cells examined in the frozen state appear to be structurally intact even when . . . animal tissue. Hence, lack of functional recovery after thawing is not proof of lack of structural preservation in the frozen state before thawing, and it is the latter . . . obtain the complete scientific literature describing the state of brains after freezing in ways which are relevant to . . . though not described adequately) after about an hour of blood reperfusion, but this defect seems
(, 54 KB)
# 14609 Perftoran: possible use in cryonics? [Igor Artyuhov]
  properties. Intravenal injections of Perftoran distinctly improved state of patients with brain or heart ischemia. It seems to me . . . Health of Russian Federation Approved by: Pharmacologic State Committee 24" June 1999 Instruction for medical . . . Perftoran from blood bed is about 24 hours. Surface-active substances are eliminated from the . . . polyglucin, reopolyglucin and oxyethylstarch. Use these solutions after the administration of Perftoran or through other
(Tue, 3 Oct 2000, 7 KB)
# 27958 whales etc. [Charles Platt]
  with organ preservation solution), SA's agreement states that the company will charge only for . . . html > Hopefully, the point is clear that brain structure and > enzymatic activity and even some brain functions survive > freezing even when freezing is done after hours of > unprotected clinical death and even with
(Sat, 20 May 2006, 5 KB)
# 4634 SCI.Re: clarifications [Mike Darwin]
  I've raised with Bob privately. However, after my last message to him on this . . . the old break less than 10 days after having a cast removed: X-rays tomorrow . . . both correct and forgive me if I state his positions wrongly. In his IMMORTALIST article Bob stated (paraphrasing) that BPI (and Alcor) have made . . . important to understand that in the ischemic brain (even after comparatively brief periods of ischemia) and especially in the profoundly ischemic brain (typical CI patient, and all too typical . . . company they have been treated by) regional brain flow becomes radically altered and some areas of the brain will receive far more perfusion than others, . . . as are some clinical investigators) that some brain injury to asanguineously perfused dogs in deep . . . my tenure at Alcor and at BPI, after loading the patient with CPA we cool . . . C. CI, by contrast, places the patient after perfusion in a sleeping bag and then . . . s sleeping bag. Rewarming took over 48 hours with most of the time being spent
(17 Jul 95 08:11:17, 18 KB)
# 5050 SCI.On Turbulence [Mike Darwin]
  the order of 4-5 C per hour) ice forms outside the cells and concentrates . . . everywhere and at once, there is a state where the crystals grow and where there . . . membranes. One resultrain tissue in the frozen state we see that axons and cell bodies . . . or cavities on EM in the frozen state or after thawing. There appears to be more tearing in the brain on examination both post thaw and by
(24 Oct 95 19:17:19, 15 KB)
# 11695 realistic cryonics [Ettinger]
  to different tissues, with the implication that "state of the art" freezing would involve teams of surgeons applying different protocols to different parts of the brain and body. I don't think even . . . just short term apparent recovery of the brain, after substantial periods of normothermic ischemia. This requirement . . . that drowning victims have made full recoveries after roughly an hour under fairly cold water. Now look at
(Fri, 7 May 1999, 5 KB)
# 4995 Memory, ischemia and freezing: let's put the discussion on the web [Ralph Merkle]
  it's clear that suspensions that start after *someone is declared dead are pointless. A . . . automatically create an appropriate page (named, perhaps, after the author and date?). If the foregoing . . . things that need doing..... Hopefully some time after the conference I'll have some free . . . that there must be substantial structural integrity after one hour of ischemia if 50% of cats recovered major spontaneous EEG activity. The neuronal state several months after the insult is not the point, the . . . types of structural damage at the one hour point. To argue that information theoretic death takes place after one hour of ischemia, it is necessary to argue . . . to look at "Molecular Repair of the Brain" at http://merkle.com/merkleDir/techFeas.html,
(Sun, 15 Oct 1995, 10 KB)
# 33149 Scoring Cases [M2darwin]
  stored at near 0 C for 24 hours, there's still a reasonable chance that their brain contains the information that cryonics tries to . . . t ideal : ideal cryonics preservation freezes the brain before an hour of cold ischemia has occurred (before that . . . current science would be to put the brain in state at low temperature that we know is . . . at all from that start. Since the brain is composed of complex molecular structures, even . . . which you make the statement: "Since the brain is composed of complex molecular structures, even . . . to exist in other humans, presumably long after you are dead? In fact, they may
(Tue, 28 Dec 2010, 10 KB)
# 5021 CryoNet #5016 - #5017 [Mike Darwin]
  Ettinger writes: >Audrey Smith's hamsters survived after about half the water in the brain was >frozen, and seemed to show normal . . . the important and devastating half, and that after this >cut-off point some cataclysmic event( . . . All I can tell you is that brains frozen to -0.5 C like those . . . t look anything like either straight frozen brains or cryoprotected brains cooled to -79 C or 196 C. . . . the REAL position pupils end up in brain death: fixed and dilated is movie nonsense: this occurs only immediately after an ischemic insult and is "extended" in . . . survived and did not show unusual behavior after >close to an hour of total brain ischemia. Later examination reportedly . . . lived" but did not survive the one hour period of ischemia. Unlike people, cats sheep, . . . human would be in a persistent vegetative state given such neuronal carnage. I have a
(20 Oct 95 18:32:52, 15 KB)
# 17623 Serious Undertakings [davidpascal]
  but CI solutions exclusively -- as he has stated. Do anonymous accusations, no motive, and no . . . cryopreservation. << Um... this is not the case. States vary slightly in terms of requirements, but in terms of controls generally, funeral directors in the United States are state-licensed, state-certified, have degreed training and study requirements, . . . beforehand for a suspension. They are paid after the patient arrives, and if the patient . . . with formaldehyde, not to say Old Spice After Shave, and someone properly perfused. When a . . . industry-wide associations. Three days of eight-hour training, and you can be a travelling . . . in implementing CI protocols properly, then CI -- after checking his qualifications -- signs him on. If . . . wisdom! >> I really do suspect that even brains poorly cryopreserved will one day be resurrected
(Thu, 20 Sep 2001, 21 KB)

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