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# 0019.4 The Technical Feasibility of Cryonics; part #4 [Ralph Merkle]
  39, pages 6-16. ---------------------------------------------------------- Determining the Healthy State In the second phase of the analysis, determination of the healthy state, we determine what the repaired (healthy) tissue . . . frozen) tissue. In determination of the healthy state, we must generate a revised structural data . . . the revised data base describes the healthy state of the tissue that we desire to . . . of the program that determines the healthy state will vary with the quality of the . . . but "equivalent" structure (e.g., an "artificial brain"). This possibility has been much discussed[11, . . . same essential character as the biological human after which it was patterned, it would indisputably . . . it is possible to build a human brain, for this has been done by traditional . . . to the traditional technique for building a brain, we might use a "guided growth" strategy. . . . of all the cells involved. The human brain has roughly 10^12 nerve cells, plus . . . insuring that the volume occupied before and after warming was the same (i.e., of . . . Of course, ice has a smaller volume after it melts. The introduction of nanovacuoles would . . . would be automatically and spontaneously digested immediately after warming. Very large increases in strength could . . . death. In the case of the human brain, the damage would have to obliterate the . . . have to remain undeveloped in practice, even after several centuries. An examination of potential future . . . watt: one joule per second One kilowatt hour: 3.6 x 10^6 joules Avogadro'
(22 Nov 92 21:17:02, 28 KB)
# 9618 The So-called Failure of the Cryonics Movement [Halperin, Jim]
  everyone I come into extended contact with. After brief discussion, nearly all seem at least . . . of tissue samples, and, if feasible, entire brains, as an incentive for organ donors. As . . . e. DNA) samples, and to accept human brains for cryonic preservation in perpetuity until identity . . . their deaths, their tissue samples and/or brains to be preserved for possible cloning and/ . . . preservation, plus an additional $500,000 for brain preservation (total $600,000). Something similar to . . . to collect tissue samples from my body after my death, and, if feasible, to remove my entire brain. At the sole option of (name of . . . to attract than the organ donation constituency? After all, both groups embrace both science and . . . that would seem a much easier sell. After all, with brain-only cryonics, storage would . . . doing it, so maybe it's acceptable after all) aspect to the common view of . . . enactment of specific cryonics laws in various states. In my opinion, this would nearly always . . . flow for at least 24 to 48 hours while families are notified. Presumably brain ischemia
(Mon, 4 May 1998, 15 KB)
# 26011 Living Will and Beyond [benbest]
  would obviously be inappropriate for the United States: old version: http://www.cryocdn.org/attorney. . . . The fact of being in a vegetative state is irrelevant. A person in cryostorage is in a vegetative state. If being on life support does not . . . would both prefer to remain in that state rather than be cryopreserved. The chances of medicine discovering a cure for the condition causing our vegetative state may be better than the chances of . . . damage -- the most serious being to the brain or the blood vessels (damage to the . . . lead to immediate deanimation -- it could take hours or days to choke to death. It . . . some means of maintaining a Cryonics Surrogate after declaration of legal death -- someone who could
(Wed, 13 Apr 2005, 6 KB)
# 8974 Re: CryoNet #8965 - #8966 [Thomas Donaldson]
  enough for storage for more than 12 hours, is presently a dream only. At a . . . revive the guinea pigs to a healthy state: all came back with widespread brain, heart, and organ damage, and did not . . . an operation may be done on the brain or the heart. Taking the temperature down . . . Hextend may even help in reviving people after the so-called "five minute limit": other
(Tue, 6 Jan 1998, 2 KB)
# 7684 Cryopreservation report (final) [Charles Platt]
  temperature of 3.2 C, a right brain surface temperature 1.8 C and left brain surface temperature of 2.2.0 degrees . . . was examined at multiple locations in both brain hemispheres and only occasionally were any aggregates . . . intravascular dye was not administered to evaluate brain perfusion status in this patient. Near the . . . on the bone abutting the forebrain. The brain was noted to be moderately dehydrated at . . . 8 degrees C. The first temperature readings after submersion in the Silcool were right brain . . . over a period of approximately 16.5 hours. The maximum surface to core temperature difference . . . C and occurred during the first two hours of cooling. Surface to core temperature differences . . . and location of ice in the cryopreserved state. Samples of spinal cord, left ventricle, and
(Thu, 13 Feb 1997, 19 KB)
# 12624 Can Organ Cryopreservation Be Achieved? [Mike Darwin]
  inferior or inappropriate tests to validate viability after cryopreservation. One of my favorites is dye exclusion where right after thawing ~90% of the cells are "alive", and if you repeat the test an hour later the number is ~10%. Guess which . . . WHICH organ are you talking about. The brain is unique, and here we have the . . . have revealed that information storage in the brain is occurring at a far higher density . . . discovered that information is stored in the brain with very high spatial density on the . . . the depth of small pieces of rat brain. To achieve this, Dodt used a microscope . . . precision. A solution was added to the brain slices which contained neurotransmitter in a special . . . Company's perfusion system which allowed 48 hour preservation. This took the pressure off, and . . . not be implemented or available until years after they are technologically and financially possible. In . . . goal has to be to improve the state of brain cryopreservation and ultimately to achieve
(Sat, 23 Oct 1999, 20 KB)
# 15259 Re: trade-offs in choosing protocols [Charles Platt]
  a comparative study, in which some dog brains were perfused using the best-available glycerol- . . . from CI of their work using sheep brains. In other words, the purpose of the . . . You don't have to be a brain surgeon to interpret these pictures. For instance an ice hole, where all brain tissue has been displaced, shredded, and/or . . . What I'll be able to do after the Singularity." 2. CryoCare Update #6. This . . . vitrification work, including preservation of two rabbit brains that were rewarmed from -80 Celsius (approx) . . . maintain near-freezing temperatures for a 7-hour (minimum) journey in summer temperatures, using a . . . thread. My personal opinion (which has been stated many times before) is that any patient
(Thu, 4 Jan 2001, 8 KB)
# 16277 KRYOS NEWS # 6 [Mgdarwin]
  are going to die soon. While this state of affairs is normally hardly an advantage, . . . a promising therapy is applied to cryopatients after legal death is properly pronounced. HIGH IMPULSE . . . to widespread clinical application outside the United States in the form of the Ambu Cardiopump: . . . chest and pull upon the chest wall after each compression with the suction cup. The . . . cup of the device is pulled up after each compression the pressure inside the chest . . . to improve blood flow to both the brain and the heart and to increase survival . . . with 18 to 20 kg of force after each downstroke of CPR. {Rabl, 1997 #45}. . . . to maintain cerebral perfusion for 55 minutes after cardiac arrest. ADDITIONAL IMPROVEMENT During the course . . . too much is removed circulation to the brain is compromised; very low blood levels of CO2 cause brain blood vessels to become constricted. In fact, . . . work -- and work for up to an hour or longer. Kryos will be using all
(Sun, 13 May 2001, 11 KB)
# 5957 BPI TECH BRIEF #18 [Mike Darwin]
  with several cryonics organizations before contacting CC, after being informed he was terminally ill. Formal . . . not had a definitive diagnosis of cancer. After more than five months of sacral pain, . . . hears hoof beats in the Western United States one generally thinks of horses, not zebras. . . . procedures and to the biopsying of his brain in exchange for reducing the basic cost . . . for cryonics. Further, in some cases the state, acting through the courts, may appropriate these . . . care cost and availability in the United States which is occurring now, should be considered . . . sentinel in this respect. A few days after his colonoscopy, the patient began to experience . . . to the left occipital lobe of the brain which was likely responsible for the right- . . . to rule out malignant involvement of the brain (the patient's family was informed of . . . in the left occipital lobe of the brain. Dr. Harris, in conjunction with the patient' . . . his concerns about possible damage to his brain from the radiation which might compromise his . . . minimal or absent blood flow (ischemia) for hours prior to cardio- respiratory arrest and pronouncement
(19 Mar 96 00:18:15, 27 KB)
# 7577 Cryonics Case History [Charles Platt]
  with several cryonics organizations before contacting CC, after being informed he was terminally ill. Formal . . . not had a definitive diagnosis of cancer. After more than five months of sacral pain, . . . hears hoof beats in the Western United States one generally thinks of horses, not zebras. . . . procedures and to the biopsying of his brain in exchange for reducing the basic cost . . . for cryonics. Further, in some cases the state, acting through the courts, may appropriate these . . . care cost and availability in the United States which is occurring now, should be considered . . . sentinel in this respect. A few days after his colonoscopy, the patient began to experience . . . to the left occipital lobe of the brain which was likely responsible for the right- . . . to rule out malignant involvement of the brain (the patient's family was informed of . . . in the left occipital lobe of the brain. Dr. Harris, in conjunction with the patient' . . . his concerns about possible damage to his brain from the radiation which might compromise his . . . minimal or absent blood flow (ischemia) for hours prior to cardio-respiratory arrest and pronouncement
(Tue, 28 Jan 1997, 27 KB)

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